摘要
目的评价一清胶囊联合盐酸多西环素胶囊治疗寻常性痤疮的疗效。方法将100例寻常性痤疮患者随机分为3组。联合治疗组34例,予盐酸多西环素胶囊100mg饭后服,2次/d,一清胶囊饭后口服2粒,3次/d,共21天;多西环素组34例,单纯口服多西环素;一清胶囊组32例,单纯口服一清胶囊,用法和用量均同联合治疗组。结果治疗结束后,联合治疗组、多西环素组及一清胶囊组的痊愈率分别为52.90%,35.30%和31.25%,有效率分别为94.10%,61.80%和59.38%。多西环素组及一清胶囊组的有效率均低于联合治疗组,差异有统计学意义(P均<0.05),多西环素组与一清胶囊组有效率差异无统计学意义(P>0.05)。联合治疗组无明显不良反应。结论一清胶囊联合盐酸多西环素胶囊治疗寻常性痤疮有效,不良反应少。
Objective To investigate the effects of doxycycline hydrochloride capsules combined with YiQing capsules on ache vulgaris. Methods One handred cases of ache vulgaris were randomly divided into three groups: combination treatment group (34 cases)were treated with doxycycline hydrochloride capsules 100mg, 2 times/d and YiQing capsules 3 times after the food, for 21 days; doxycycline hydrochloride group (34 cases )were treated with doxycycline hydrochloride capsules 100mg, 2times/d after the food for 21 days, Yiqing capsules group (32 cases) YiQing capsules 3 times/d, after the food for 21 days. Results The clinical cure rate of combination treatment group, doxycycline hydrochloride group, Yiqing capsules group were 52.90%, 35.30% ,31.25%, and the total effective rate were 94.10% ,61.80% ,59.38%. Total effectiveness of Doxycycline Hydrochloride group and Yiqing Capsules group were significant difference between combination treatment group (P 〈 0.05 ). The Doxycycline Hydrochloride group and Yiqing Capsules group were no significant difference( P 〉 0.05 ). The combination treatment group without obvious adverse reactions. Conclusion YiQing Capsules combined with Doxycycline Hydrochloride capsules for the treatment of ache vulgaris effective, few side-effect.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2011年第5期406-407,共2页
The Chinese Journal of Dermatovenereology
关键词
痤疮
一清胶囊
盐酸多西环素胶囊
Acne vulgaris
YiQing Capsules
Doxycycline hydrochloride capsules