摘要
目的 比较DDMO-100S膜肺与Terumo SX-10膜肺用于小儿体外循环的气体交换与复温的性能.方法 选择3～12岁先天性心脏病患儿39例,拟在体外循环下行房室缺修补术,随机分为DD组（n=21）和SX组（n=18）,DD组用DDMO-100S膜肺（西安岱岱,中国）,SX组用Terumo SX-10膜肺（Terumo,日本）.采用中低温中高流量CPB,冠脉灌注冷晶体停跳液.于转机后15 min和停机前5 min抽取动脉血行血气分析,并计算氧合指数（OI）（OI=PaO2/FiO2）.监测鼻咽温度并记录复温时间.结果 实际总预充量DD组＞SX组[（742.5±107.3）ml vs（531.3±84.3ml）,P＜0.05];两组转机后15 min停机前5 min的PO2、PCO2和氧合指数（OI）差异无统计学意义（P＞0.05）;两组复温时间差异无统计学意义[（31.5±10.2）min vs（30.6±8.2）min,P＞0.05].结论 在观察条件下,DDMO-100S膜肺和Terumo SX-10膜肺的气体交换与复温的性能相当,实际总预充量稍大.
Objective To compare the gas and heat exchange performance of membrane oxygenator DDMO-100S and membrane oxygenator Terumo SX-10 in cardiopulmonary bypass（CPB）in children.Methods 39 children aged 3-12 yrs who suffered from congenital heart disease were selected,and the repair of ventricle septal defect or/and atrial septal defect was performed under cardiopulmonary bypass.The 39 children were randomly divided into Group DD（n =21）and Group SX（n = 18）.Membrane oxygenator DDMO-100S（Made by Xi＇an Daidai,China）was used in Group DD and Membrane oxygenator Terumo SX-10（Made by Terumo,Japan）in Group SX,respectively.The hypothermic cardiopulmonary bypass with high perfusion flow and the cool crystalloid cardioplegia were applied in all children.The artery blood samples were taken for measuring PO2 and PCO2 and the oxygenating index（OI）was calculated by the formulae（OI = PaO2/FiO2）.The temperature at nasal pharynx was monitored and the rewarming time was recorded.Results The total priming volume in Group DD was bigger than in Group SX [（742.5 ± 107.3）ml vs（531.3 ± 84.3）ml,P 〈 0.05].The PO2,OI and PCO2 at 15 min after CPB or at 5 min before cease of CPB had no differences in both group（P 〉0.05）.The rewarming time had no difference in both group [（31.5 ± 10.2）min vs（30.61 ± 8.2）min,P 〉0.05].Conclusions Under our observation condition,the gas and heat exchange performance of membrane oxygenator DDMO-100S were the same as membrane oxygenator Terumo SX-10,when it was used in cardiopulmonary bypass in children,but it had a little bit more priming volume.
出处
《中国医师杂志》
CAS
2011年第3期328-330,共3页
Journal of Chinese Physician
关键词
体外膜氧合作用/方法
体外循环
复温
Extracorporeal membrane oxygenation/MT
Extracorporeal circulation
Rewarming
