摘要
检索Pubmed数据库和万方数据库以及中国期刊全文数据库文献,分析膜式氧合器的特点。结果表明现在人工肺的应用主要是分离膜式,其形式已从最初的卷筒式、平板折叠式发展到今天广为采用的微孔中空纤维膜式。中空纤维膜氧合器使用中空纤维膜作为交换的主要场所,完成氧气和二氧化碳的交换,由于其在交换面积、氧合形态等方面具有优势,近年来已经成为人工肺研究的主要方向。用于制造中空纤维的材料主要为一些成纤性能良好的高分子材料,对膜材料的要求是具有良好的成膜性、热稳定性、化学稳定性、耐酸碱性、微生物侵蚀性和抗氧化性。当前的研究主要是为了提高气体交换能力和提高生物相容性,采用的方法主要有改进膜材料,优化设计以及对各种性能的实验评估和临床评价。
A computer-based online search of Pubmed, Wanfang database and Chinese Journal Full-text Database was undertaken to identify literature and analyze characteristics of membrane oxygenator, Separation membrane, commonly used for artificial lung, has developed from drum, plate folding pattern to microporous hollow fiber membrane. In microporous hollow fiber membrane oxygenator, the hollow fiber membrane is the main place that transition occurs from oxygen to carbon dioxide. Because of the advantages in transition area and oxygenation form, it has become main study direction of artificial lung recently, Hollow fiber is mainly composed of high polymer materials with good fibrogenic capability, and membrane materials with good membrane-forming ability, heat stability, chemical stability, acid and alkali resistance, microbe erosion and antioxygenation. Current studies focus on how to improve gas exchange ability and biocompatibility, such as to improve membrane materials, optimize design and experimental and clinical evaluation of performance,
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2008年第10期1927-1930,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
