摘要
目的:研究2型糖尿病患者病程、空腹C肽水平、骨密度与血清胰岛素样生长因子-2(IGF-2)的关系。方法:96例2型糖尿病患者,均测量身高、体质量、骨密度、骨密度以及空腹血清C肽和IGF-2水平。分析糖尿病病程、IGF-2、骨量以及空腹C肽水平之间的关系。结果:随着糖尿病病程延长,IGF-2水平下降;随着骨密度水平下降,IGF-2水平下降;随着空腹C肽水平下降,IGF-2水平下降。结论:IGF-2可能参与了2型糖尿病的进程和骨质疏松的发生。
Objective:To study the relationship between the serum level os insulin-like growth factor 2(IGF-2) and bone mineral density(BMD) in patients with type2 diabetes(DM).Methods:Height,weight,fasting serum C-peptide,IGF-2,and BMD were measure in 96 patients with DM.The associations among the levels of IGF-2,C-peptide and BMD were analyzed.Results:As the years of being DM gets longer,the level of IGF-2 gets lower.BMD was positively related with the lever of IGF-2.When the level of C-peptide decreased,the level of IGF-2 tended to be lower.Conclusions:IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.
出处
《中国临床医学》
2011年第2期196-197,共2页
Chinese Journal of Clinical Medicine