摘要
目的初步探讨磁共振全身弥散加权成像(whole body diffusion weighted imaging,WB-DWI)在恶性肿瘤筛查中的应用价值。方法对临床疑似恶性肿瘤患者36例及10例正常健康志愿者行磁共振全身弥散加权成像,并于1周内对可疑部位行常规MRI检查(胸部病变加做CT),必要时增强扫描。诊断结果与病理及/或临床综合评价结果进行对照。结果 36例患者最终诊断恶性肿瘤29例,良性病变7例。WB-DWI诊断恶性肿瘤28例,误诊1例,漏诊2例,其中20例患者发现了原发病灶,诊断敏感度93.1%,特异度85.7%,约登指数0.79,符合率91.7%。同时,WB-DWI还发现了6例良性病变的异常影像。结论全身弥散加权成像在恶性肿瘤筛查中具有一定价值。
Objective：To evaluate the value of whole-body magnetic resonance diffusion weighted imaging（WB-DWI） in the screening of malignant tumor.Materials and Methods：Ten healthy volunteers and 36 patients of clinically suspected malignant tumors underwent WB-DWI and conventional MRI（scanning CT if it is chest disease） enhancing the scanning when necessary.The medical results of WB-DWI and MRI/CT were compared with the findings of pathological diagnosis and clinical comprehensive evaluations.Results：Twenty-nine of 36 patients were diagnosed as malignant tumors by final pathological endings,the others were benign lessions.Twenty-eight of 36 patients were diagnosed as malignant tumors by WB-DWI,1 were misdiagnosed,2 were missed.The primary lesions of 20 patients were diagnosed by WB-DWI.The sensitivity,specificity,youden’s index and agreement/consistency rate were 93.1%,85.7%,0.79 and 91.7%.Six of 7 patients,abnormality of benign lesions were found by WB-DWI.Conclusion：WB-DWI have certain value in the screening of malignant tumor.
出处
《磁共振成像》
CAS
2011年第3期205-209,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
山西省卫生厅科技攻关计划项目(编号200901)资助
关键词
磁共振成像
全身弥散加权成像
恶性肿瘤
筛查
Magnetic resonance imaging； Whole body diffusion weighted imaging； Malignant tumor； Screening；
