摘要
目的探讨单壁碳纳米管与碘化钠反应后C-I共价键的生成及其表征,为单壁碳纳米管放射性碘标记及观察其在生物体内分布提供实验参考数据。方法采用Iodogen方法制备碘化的单壁碳纳米管(I-SWCNTs),然后用透射电子显微镜(TEM)及X射线光电子能谱仪(XPS)对碳碘结合及C-I共价键的形成进行表征。结果 TEM成像和成分分析显示,与未经处理的SWCNTs对比,处理后的产物其管壁不再光滑,有缺口,其上结合有碘。XPS检测发现,碘与SWCNTs形成C-I共价键,处理后产物的碘电子结合能与具有C-I共价键的参考物硝基碘苯基本一致,而与具有离子性质的NaI的结合能不同。结论用Iodogen法能使SWCNTs与NaI结合生成C-I共价键。
Objective To explore the formation and characterization of C-I covalent bond between the single-wall carbon nanotubes（SWCNTs） and NaI in order to provide experimental reference data for radioiodination of SWCNTs and oberving its biodistribution.Methods Iodogen method was used to synthesize iodinated SWCNTs（I-SWCNTs） in which iodine was covalently bound to SWCNTs.The formation of C-I bond was proved by transmission electron microscope（TEM） as well as X-ray photoelectron spectroscopy（XPS）.Results The image and component analyses TEM showed that the wall of the tubes of I-SWCNTs became rough,with gaps,and bound iodine,as compared to that of the untreated products.XPS spectra showed that the binding energy of iodine of I-SWCNTs was analogous to that of nitroiodobenzene and different from that of ionic NaI.Conclusion The C-I covalent bond between the single-wall carbon nanotubes and NaI could be formed by the Iodogen method.
出处
《解放军预防医学杂志》
CAS
2011年第2期81-85,共5页
Journal of Preventive Medicine of Chinese People's Liberation Army
基金
国家自然科学基金课题(No.20877102)国家自然科学基金课题(No.20907075)
关键词
单壁碳纳米管
C-I共价键
透射电子显微镜
X射线光电子能谱
碘化钠
single wall carbon nanotubes
C-I covalent bond
transmission electron microscope
X-ray photoelectron spectroscopy
sodium iodide.
