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瑞格列奈与二甲双胍联合治疗90例2型糖尿病的疗效观察 被引量:7

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摘要 目的观察瑞格列奈与二甲双胍联合治疗对90例2型糖尿病的血糖及血脂代谢的影响。方法采用开放式研究,治疗前后自身对照,服用瑞格列奈片(0.5~1)mg/次,每天3次,饭前15min服用;二甲双胍片(0.25~0.5)g/次,每天3次,饭时或饭后服用,疗程12周;检测治疗前后空腹血糖,糖化血红蛋白以及血脂。结果治疗前空腹血糖(9.87±1.56)mmol/L,治疗12周后空腹血糖为(6.22±0.85)mmol/L,治疗前糖化血红蛋白为(9.34±1.22)%,治疗12周后糖化血红蛋白为(6.51±0.68)%,治疗前甘油三酯为(2.42±1.06)mmol/L,治疗12周后甘油三酯为(2.11±0.86)mmol/L,治疗前低密度脂蛋白为(3.34±0.67)mmol/L,治疗12周后低密度脂蛋白为(3.25±0.54)mmol/L。结论瑞格列奈与二甲双胍联合治疗2型糖尿病疗效明显,不良反应少,患者耐受性好,具有临床应用价值。
出处 《中国现代医生》 2011年第14期48-49,共2页 China Modern Doctor
基金 浙江省义乌市2009年第一批科研计划项目(编号:09-3-06 项目名称:社区糖尿病规范化管理研究)
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