期刊文献+

负压封闭引流技术治疗爆炸伤致猪全层腹壁缺损的实验研究 被引量:2

Research of treating blast injury wound-induced abdominal wall defects in pigs with vacuum sealing drainage
下载PDF
导出
摘要 目的:探讨负压封闭引流技术(Vacuum Sealing Drainage,VSD)对于爆炸伤导致的全层腹壁缺损后的疗效。方法:20只健康家猪制作腹部爆炸伤开放模型随机分为两组。所有创面均在伤后6~8h内清创,实验组将带孔硅胶膜覆盖于脏器表面后应用VSD敷料进行治疗,压力设定于-125mmHg,对照组将硅胶膜覆置于脏器表面,盐水纱布覆盖包扎,常规换药,比较两组修复前时间,换药次数,创面及腹腔感染率。结果:实验组修复前时间为(7.20±2.39)天,换药次数为(2.20±0.79)次,创面及腹腔感染率为10%;对照组修复前时间为(10.30±2.11)天,换药次数为(11.90±2.23)次,创面及腹腔感染率为70%。两组各项比较均有统计学意义(P<0.05)。结论:VSD治疗对于爆炸伤导致的全层腹壁缺损能缩短治疗时间,有效控制创面及腹腔感染,减少换药次数。 Objective To explore the effects of vacuum sealing drainage(VSD) for blast injury wound-induced abdominal wall defects in pigs.Methods Twenty small white domestic pigs models of exlposive abdominal wounds were divided into two groups.All wounds were debrided within 6-8 hours of injury.Group A set the pressure at-125mmHg,VSD therapy was applied to the abdomen by placing a fenestrated silicone sheeting over the abdominal viscera.Group B treated with silicone sheeting,which was covered with a salinesoaked gauze dressing that was changed several times daily.Duration of treatment,days of preoperation,times of dressing,the ratio of soft tissue infection and intraabdominal infection were compared between two groups.Results In VSD group,days of preoperation were(7.20±2.39)days,times of dressing were(2.20±0.79),the ratio of soft tissue infection was 10%,intraabdominal infection was 10%.In non-VSD group,days of preoperation were(10.30±2.11)days,times of dressing were(11.90±2.23),the ratio of soft tissue infection was 70% intraabdominal infection was 70%.There were significant differences in the preoperative days,dressing times,the ratio of soft tissue infection and intraabdominal infection between 2 groups(P0.05).Conclusion It is effective to apply VSD to management blast injury would-induced abdominal wall defects,which can shorten the preoperative days,cut down infection rate,decrease times of dressing.
出处 《中国美容医学》 CAS 2011年第3期421-424,共4页 Chinese Journal of Aesthetic Medicine
基金 全军医药卫生科研基金(项目编号08G116)
关键词 封闭负压引流 爆炸伤 腹壁缺损 VSD(Vacuum Sealing Drainage) blast injury abdominal wall defects
  • 相关文献

参考文献12

  • 1Hayter JP,Cawood JI.Oral rehabilitation with endosteal implants and free flaps[J].Int J Oral Maxillofac Surg,1996,25(1):3-12. 被引量:1
  • 2何黎升,周树夏,刘宝林.种植体在下颌骨缺损功能重建中的应用[J].国外医学(口腔医学分册),1993,20(4):226-229. 被引量:8
  • 3Zvi Artzi,Haim Tal.Mucosal considerations for osseointegrated implants[J].J Prosth Dent,1993,70(5):427-432. 被引量:1
  • 4Chi-ying Tsai,Minoru Ueda,Ken-ichiro Hata-Clinical results of cultured epithelial cell grafting in the oral and maxillofacial region[J].J Cranio Maxillofac Surg,1997,25(1):4-8. 被引量:1
  • 5Ten Brugenlcate CM,Kreceler G,Van der Kwast WAN,et al.Palatal mucosal grafts for oral implant devices[J].Oval Surg Oval Mod Oval Pathol,1991,72(2):154-158. 被引量:1
  • 6Haers PEJ,van Straaten W,Stoelinga PJW,et al.Reconstruction of the severely resorbed mandible prior to vestibuloplasty or placement of endosseous implants.A 2 to 5 year follow-up[J].Int J Oral Maxillofac Stag,1991,20(3):149-154. 被引量:1
  • 7潘瑾,张益,林野,俞光岩.下颌骨缺损自体骨移植术后种植床软组织条件的评估与准备[J].中国口腔种植学杂志,2003,8(2):54-56. 被引量:2
  • 8Chang YM,Chan CP,Shen YF,et al.Soft tissue management using palatal mucosa around endosteal implants in vascularized composite grafts in the mandible[J].Int J Oral Maxillofac Surg,1999,28(5):341-343. 被引量:1
  • 9Shabram Nazerani,Hossein Behnia,Mobammad Hosein Kalantar Motamedi.Experience with the prefabricated free fibula flap for reconstruction of maxillary and mandibular defects[J].J Oral Maxill ofac Surg,2008,66(2):260-264. 被引量:1
  • 10Vinzm KG,Holle J,Wuringer E,et al.Prefabricationofcombinedscapula flapsformicrosurgicalreconstructioninoro-maxillofacialdefects:anew method[J].JCranio-Maxillofac Surg.1996,24(4):214-223. 被引量:1

二级参考文献37

  • 1刘宝林,希扬,陈青,马伟光,马轩祥,郑粦华,袁井圻,金同春,司徒镇强,周树夏,徐君伍.骨融合式种植体在下颌骨缺损义齿修复上的应用[J].实用口腔医学杂志,1989,5(2):71-72. 被引量:15
  • 2李娅芳,邓英杰,刘书琴,缪硕宁,韩丽梅,张寒煦.透皮吸收制剂研究进展[J].中国药学杂志,1997,32(1):3-7. 被引量:35
  • 3乐文.到2003年透皮给药产品市场将达91亿美元[J].国外药讯,1994,7:6-6. 被引量:1
  • 4许景峰 赵维娟 张梅 等.31种药物的理化因素对透皮速率的影响[J].军队医药杂志,1997,7(2):40-40. 被引量:4
  • 5国际药学文摘,2000,0137. 被引量:1
  • 6国际药学文摘,2000,3711. 被引量:1
  • 7Ilango R. Formulation and Evaluation of transdermal preparation of nimesulide gel. East Pharmacy, 1998,41 : 123 (Nov). 被引量:1
  • 8Touitou E. L ipo somes as carriers fer top ical and transdermal de-livery. J Phann Sci, 1994,83 (9) : 1189. 被引量:1
  • 9Maia CS. Solid lipid nanoparticles as drug carrier for topical glucocorticoid. Int J Pharm,2000,196 (2) : 165. 被引量:1
  • 10Hao JS,L i D, L I S,et al. The effect of some penetration enhancers on the transdermal iontopho retic delivery of insulin in vitro. J Clin Pharm Sci,1996,5(2) : 88. 被引量:1

共引文献28

同被引文献24

引证文献2

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部