摘要
目的:评估短时受精联合早期补救卵胞浆内单精子显微注射(R-ICSI)在完全受精失败周期的临床价值。方法:2009年1月～2010年6月我中心试管婴儿助孕治疗709例,其中短时受精完全失败行早期R-ICSI周期82例,卵胞浆内单精子显微注射(IC-SI)周期627例,比较两组正常受精率、异常受精率、优质胚胎率、胚胎种植率、临床妊娠率及流产率。结果:两组正常受精率、优质胚胎率、胚胎种植率、临床妊娠率及流产率无统计学差异,R-ICSI组异常受精率(5.0%)显著高于ICSI组(3.0%)(P<0.05)。结论:短时受精联合早期R-ICSI可及早发现受精失败并及时补救,获得较好的临床结局。
Objective：To evaluate the clinical outcome of the combination of short-period fertilization with early rescue intracytoplasmic sperm injection（R-ICSI）after complete failure of in vitro fertilization（IVF）.Methods：From Jan 2009 to June 2010,709 fresh cycles of assisted reproductive techniques were analyzed,including 82 cycles R-ICSI and 627 cycles of intracytoplasmic sperm injection（ICSI） at the same period.The normal fertilization rate,abnormal fertilization rate,high-quality embryo rate,embryo implantation rate,clinical pregnancy rate and abortion rate were compared.Results：There was no statistically difference between R-ICSI and ICSI in normal ferti1ization rate,high-quality embryo rate,embryo implantation rate,clinical pregnancy rate and abortion rate,but there was statistically difference between them in abnormal fertilization rate（5.0% vs 3.0%）（P0.05）.Conclusion：The combination of short-period fertilization with R-ICSI can find and rescue fertilization failure timely and get better clinical effect.
出处
《现代妇产科进展》
CSCD
北大核心
2011年第3期218-220,共3页
Progress in Obstetrics and Gynecology
关键词
卵胞浆内单精子显微注射
补救
受精失败
短时受精
Intracytoplasmic sperm injection
Rescue
Fertilization failure
Short-period fertilization
