摘要
目的:探讨不明原因不孕患者体外受精方式的选择。方法:将每例不明原因不孕患者(35例)超促排卵获取的卵母细胞随机分为二组,分别行常规体外受精(A组)和ICSI受精(B组),比较二组的受精结局、妊娠率及着床率。结果:A组受精率(51.2%)低于B组(61.3%,P<0.05);而完全受精失败率(20.0%)明显高于B组(2.8%,P<0.05);二组的优质胚胎率、临床妊娠率、着床率无差异。结论:不明原因不孕患者行首次IVF治疗时,采用部分卵母细胞常规受精、部分卵母细胞ICSI的方法,可降低完全受精失败风险。
Objective：To explore the selection of the insemination methods for patients diagnosed with unexplained infertility. Methods： In 35 couples with unexplained infertility undergoing IVF, sibling oocytes were randomized into conventional in vitro fertilization （IVF, group A） or intracytoplasma sperm injection （ICSI, group B） insemination. Fertilization rate and embryo quality were compared between group A and group B. Results： A significantly better fertilization rate was obtained after ICSI as compared with conventional IVF （61.3 % vs 51.2%, P〈0.05）, and total fertilization failure rates following ICSI and IVF treatment were 2.8% and 20%, respectively （P〈0.05）. There was no statistically significant difference in embryo quality, pregnancy rate and implantation rate between graoup A and group B. Conclusion： In the first IVF cycle of couples with unexplained infertility, splitting the sibling oocytes by IVF and ICSI can effectively minimize complete fertilization failure.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2008年第5期264-267,共4页
Reproduction and Contraception
