摘要
目的探讨原发干燥综合征中枢神经系统损害(CNS-PSS)的MRI表现,提高对CNS-PSS的MRI表现的认识。资料与方法搜集经临床证实的14例CNS-PSS患者的临床和影像学资料进行回顾分析。结果 14例患者中,5例脑内病变,4例脊髓病变,3例脑内合并脊髓病变,1例脑膜炎,1例脑积水。脑内病变多发生于白质,较少累及皮质,仅1例小脑病灶累及灰质,但病灶主体仍位于白质。脑内7例为多发病灶,1例为单发病灶。脊髓6例为单发病灶,1例为多发病灶。脑内及脊髓内病灶T1WI呈稍低信号,T2WI呈较高信号。除1例脑膜炎患者外有6例患者行增强检查,仅1例脊髓内病变边缘可见强化。结论 CNS-PSS可累及脑及脊髓,脑内病变主要累及白质,MRI表现多为稍长T1、较长T2信号,增强扫描大多无明显强化;CNS-PSS的MRI表现缺乏特异性,需结合临床及实验室检查进行诊断。
Objective To evaluate the MRI features of the central nervous system complication in primary Sjogren syndrome（CNS-PSS）.Materials and Methods MRI images of 14 patients with primary Sjogren syndrome associated with central nervous system complication were analyzed retrospectively.Results In 14 cases,5 cases were brain lesions,4 cases were spinal cord lesions,3 cases were cerebral and spinal lesions,complicated with meningitis in 1 patient,hydrocephalus in 1 patient.The lesions mostly located in white matter,less involved gray matter,and only one lesion involved the gray matter.The lesions showed high signal intensity on T2WI and low signal intensity on T1WI.Six patients performed enhanced MRI examination with Gd DTPA injected,and only one lesion showed enhancement on the edge.Conclu-sion CNS-PSS can affects brain and spinal cord,mainly involving white matter.The MRI features include high signal intensity on T2WI and low signal intensity on T1WI.The lesions won＇t show obvious enhancement after injected Gd-DTPA.CNS-PSS lack of specificity MRI features,which need to combine with clinical and laboratory examination to make diagnosis.
出处
《临床放射学杂志》
CSCD
北大核心
2011年第3期313-316,共4页
Journal of Clinical Radiology
关键词
原发干燥综合征
磁共振成像
中枢神经系统
Primary sjogren syndrome Magnetic resonance imaging Central nervous system
