摘要
目的探讨微波消融(PMCT)治疗中晚期肝癌对肝纤维化五项指标的影响。方法 49例微波消融的原发性肝癌患者,观察治疗前后血清HA、LN、PC-Ⅲ、Ⅳ-C、TGF-β1五项肝纤维化指标水平。结果 PMCT治疗后与PMCT治疗前相比,HA、LN、PC-Ⅲ、Ⅳ-C差异无统计学意义,TGF-β1每次均有下降(P<0.05)。结论 PMCT治疗原发性肝癌对HA、LN、PC-Ⅲ、Ⅳ-C无影响,且对肝纤维化有一定抑制作用。
Objective To study the influence of the percutaneous microwave coagultion therapy(PMCT) on five hepatofibrosis indexes of middle and advanced hepatocellular carcinoma.Methods Forty-nine cases of primary hepatocellular carcinoma(massive type or nodular type) who had received curation of PMCT,hepatofibrosis index levels of serum HA、LN、PC Ⅲ、IV-C、TGF-β1 were observed before and after therapy.Results No significance difference was observed in relation to HA、LN、PC Ⅲ、IV-C of patients before and after every duration of PMCT.But the TGF-β1 was continuously reduced(P0.05).Conclusion The HA、LN、PC-Ⅲ、Ⅳ-C were not significantly changed after PMCT,but the TGF-β1 was continuously reduced.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2011年第3期322-323,共2页
Cancer Research on Prevention and Treatment
关键词
原发性肝癌
微波消融
肝纤维化
Primary hepatocellular carcimona
PMCT
Hepatofibrosis