摘要
目的:检测血清前白蛋白(PA)、胆碱酯酶(ChE)、单胺氧化酶(MAO)的活力变化规律,从而探讨其对肝硬化患者的临床意义。方法:临床确诊的肝硬化患者106(男62,女44)例,平均年龄(55±8)岁,其中肝硬化代偿期患者73例(男49例,女24例,平均年龄52±5岁),失代偿期患者33例(男21例,女12例,平均年龄54±6岁)。用免疫比浊法测定PA含量,用连续监测法测定CHE活性,用酶动力学法测定MAO活力,并与健康对照组比较。结果:肝硬化代偿期、失代偿期患者血清PA含量、ChE活力较正常对照明显下降(P<0.01)。代偿期患者MAO活力升高无统计学意义(P>0.05),失代偿期MAO升高有统计学意义(P<0.05)。结论:测定PA、ChE、MAO三者水平可以作为肝硬化患者病情监测的有效指标。
Objective To explore the change of prealbumin（PA）, cholinesterase（ChE） and monoamine oxidase（ MAO ） serum 1 evels in the patients with cirrhosis.Methods One hundred and six patients with liver cirrhosis and 55 ages - matching healthy person were selectee as cases and controls respectively. The PA content was measured with immunoturbidimetry and ChE and MAO were detected by reaction rate methee.Resuhs The PA and ChE concentration decreased significantly inpatients with compensated and uncompensated cirrhosis compared with controls（ P 〈 0.01, respectively）. However, patients with decompensated cirrhosis had significantly higher levels of MAO compared to patients with compensatee cirrhosis and healthy controls（ P 〈 0.05）. Conclusion To detect the serum levels of PA, ChE and MAO may have great help in the diagnosis of liver cirrhosis.
出处
《内蒙古中医药》
2011年第3期3-3,共1页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
肝硬化
前白蛋白
胆碱酯酶
单胺氧化酶
Liver cirrhosis
Prealhumin
eholinesterase
Monoamine oxidase
