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大理地区广州管圆线虫病暴发42例诊治分析 被引量:4

Diagnosis and treatment of 42 angiostrongyliasis cases in Dali Prefecture
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摘要 目的探讨广州管圆线虫病的临床特点,诊治方法、疗效以及感染源。方法回顾性分析42例广州管圆线虫病患者的临床表现、实验室检查资料、诊治情况以及开展流行病学调查。结果广州管圆线虫病的临床表现复杂多样,但以头痛为主征;血白细胞可正常(28例,66.67%)或升高(14例,33.33%),大部分病例血嗜酸性细胞升高(31例,73.81%);全部病例脑脊液白细胞数、嗜酸性细胞均升高,但少部分病例脑脊液嗜酸性细胞早期并不升高;早期误诊率高(42.8%);用阿苯哒唑治愈率100%,药物主要不良反应是肝脏损伤;流行病学调查证实是一起输入性暴发事件。结论大理地区广州管圆线虫病全部为输入性病例,头痛为其主要临床表现,早期易误诊,血液、脑脊液中嗜酸性细胞升高为特征性改变,是诊断的主要依据,阿苯哒唑治疗安全有效。 Aim To discuss the clinical characteristic,the diagnosis method,the therapeutic effect and the source of infection of angiostrongyliasis. Methods The linical manifestations, results of diagnosis of 42 angiostrongyliasis patients were analyzed. Results The manifestationa of 42 angiostrongyliasis cases were diverse and headache predominated. The WBC count elevated in 33.33% of them and eosinophils elevated in 73.81% of them in addition to the elevation of the number of cerebmspinal fluid WBC and the eosinophils. The early misdiagnositic rate was as high as 42.80%. The Cure rate of albendazole was 100%. The main side effect was damage to the liver. Epidemiological survey showed this event was an imported infection. Conclusion All the angiostrongyliasis cases were imported infections,healdach is the main manifestation and the elevation of WBC and eosinophils in blood and cerebralspinal fluid is the evidence for making diagnosis. Albendazole is effective for treatment of angiostrongyliasis patients.
出处 《中国热带医学》 CAS 2011年第4期430-431,共2页 China Tropical Medicine
关键词 广州管圆线虫病 头痛 嗜酸性细胞 阿苯哒唑 Angiostrongyliasis Headache Eosinophils Albendazole
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