摘要
目的通过对妊娠妇女阴道分泌物进行分离培养及药敏试验,了解妊娠妇女念珠菌的感染情况及其对常用抗真菌药物的敏感性。方法用科玛嘉念珠菌显色培养基对阴道分泌物进行培养,ATB半自动微生物培养鉴定仪对分离的菌株进行鉴定和药敏分析。结果分离念珠菌256例,主要是白色念珠菌。所有分离的念珠菌对两性霉素B和5-氟胞嘧啶敏感,对伊曲康唑、伏立康唑、氟康唑有一定程度的耐药。结论妊娠妇女阴道念珠菌感染以白色念珠菌为主,对于唑类抗生素的耐药性呈现一定程度的上升趋势,应加强念珠菌的检测和药物敏感分析。
Objective To investigate the etiological characteristic and susceptibility to common antifungal drugs in pregnant women by species identification and antibiotic susceptibility studies on isolates from the patients＇ vaginal secretion. Methods CHROM and ATB semi-automatic identification system were used to identify species from patients＇ vaginal secretion. Results There were 256 strains of candida isolated,mostly were Candida albicans.All isolated strains were susceptive to amphotericin B and 5-FC,and had drug resistance to VRC,ITR,and FCA to some extent. Conclusions Vaginal candidiasis is usually caused by Candida albicans and drugresistance to zole antibiotics increases,which means that the detection and drug susceptibility analysis of candida should be strengthened.
出处
《实用预防医学》
CAS
2011年第3期480-481,共2页
Practical Preventive Medicine
关键词
妊娠妇女
阴道分泌物
白色念珠菌
耐药性
Pregnant women
Vaginal secretion
Candida albicans
Drug resistance
