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蒲地蓝联合利巴韦林治疗小儿手足口病疗效观察 被引量:4

The clinical effect of Pudilan combined with ribavirin in treatment of children with HFMD
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摘要 目的 观察蒲地蓝联合利巴韦林对手足口病的治疗效果.方法 手足口病患者70例,随机分为两组:治疗组(蒲地蓝联合利巴韦林)和对照组(单用利巴韦林).观察两组患者的疗效、皮疹完全消失时间、发热消退时间及不良反应.结果 治疗组治愈率及有效率分别为57%、94%,对照组治愈率及有效率分别为43%、86%,两组治愈率及有效率比较差异有统计学意义(均P<0.05).治疗组较对照组在手足皮疹消失、口腔皮疹消失及发热消退时间明显缩短,差异有统计学意义(均P<0.05).两组患者均未发现明显不良反应.结论 较单用利巴韦林,蒲地蓝联合利巴韦林治疗手足口病明显提高了治愈率,缩短了皮疹完全消失时间及发热消退时间,是治疗手足口病的一种安全、有效的方法. Objective To investigate the effect of Pudilan combined with ribavirin in treatment of the hand-foot-mouth disease(HFMD). Methods 70 patients were randomly divided into treatment group ( Pudilan combined with ribavirin) and control group (ribavirin only). Results Compared with the control group,the cure rate and the effective rate in treatment group had statistically significant difference ( all P < 0.05 ). Compared with the control group,the rash disappeared time and the fever subsiding time in treatment group were shorter obviously ( all P <0. 05 ). The both groups had no obvious side effect. Conclusion Pudilan combined with ribavirin in the treatment of HFMD had a good therapeutic effect and were a safe and effective method.
作者 钟晓波
出处 《中国基层医药》 CAS 2010年第24期3327-3328,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 蒲地蓝 利巴韦林 手足口病 Pudilan Ribavirin Hand-foot-mouth disease
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