摘要
本研究探讨80岁以上老年急性白血病的临床特点。对我院2000-2010年收治的12例80岁以上急性白血病患者进行回顾性分析,其中9例急性髓系白血病,3例急性淋巴细胞白血病,均合并有多种基础疾病,大部分患者一般情况较差,接受了个体化治疗方案的患者共10例。结果表明,2例患者获得完全缓解,其余患者未获得缓解。平均生存时间20±16周。AML患者平均生存时间为27±14周,明显长于国外报道。生存期最短的3例均为ALL患者。结论:本组高龄AML患者采取个体化治疗,生存期得到明显延长。而高龄老年ALL患者则预后很差,缺乏相对有效的治疗措施。
The objective of this study was to explore the clinical features of acute leukemia patients aged over 80 years.12 cases of acute leukemia patients aged over 80 years who were diagnosed from 2000 to 2010 years were analyzed retrospectively.9 caseas suffered from acute myelogenous leukemia and 3 cases were with acute lymphoblastic leukemia.All patients were with several complicated diseases and the general status was poor in most patients.10 cases received individualized treatments.The results showed that 2 patients achieved complete remission,but in other patients was not observed remission and the mean survival time was 20±16 weeks.In AML patients,the mean survival time was 27±14 weeks which was obviously longer than that in other reports.The survival time in 3 ALL patients was shortest.In conclusion,survival time was prolonged obviously in AML patients well advanced of age after individualized treatments,but prognosis of ALL in aged patients was very poor,for whom there is no relatively effective treatment.
出处
《中国实验血液学杂志》
CAS
CSCD
2011年第1期139-142,共4页
Journal of Experimental Hematology
