摘要
目的探讨对调强放射治疗对高龄老年食管癌患者的疗效及其预后的相关因素。方法回顾性分析自2007年6月至2010年3月进行调强放射治疗的51例高龄老年食管癌患者的生存率、预后影响因素和对不良反应的耐受性。结果调强放射治疗后总有效率为82.4%,随访1、2、3年总生存率分别为76.5%、53.0%、35.3%。大多数患者都能对调强放疗的不良反应耐受,而患者死亡的主要原因则是肿瘤局部未控、复发和转移。结论对于高龄老年食管癌患者来说,调强放射治疗近期疗效显著,患者对不良反应的耐受性好,不失为一种行之有效的治疗方法。
Objective To investigate the efficacy and influencing factors of intensity modulated radiation therapy(IMRT) in elderly esophageal carcinoma patients.Methods Fifty-one elderly esophageal carcinoma patients were treated with IMRT from June,2007 to March,2010.Survival rate,prognostic influencing factors and tolerance to toxic side effects were analyzed retrospectively.Results After IMRT,the total effect rate was 82.4%.The first,second and third year overall survival rates were 76.5%,53.0% and 35.3% respectively.Most patients could endure the toxic side effects of IMRT.Local uncontrollableness,recurrence and metastasis of tumor were the main causes for the death.Conclusions IMRT is an efficient and well tolerated way of treating elderly esophageal carcinoma patients.
出处
《中国肿瘤临床与康复》
2013年第8期882-884,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
调强放射治疗
老年
食管癌
预后
Intensity modulated radiation therapy(IMRT)
Elderly patients
Esophageal canc er
Prognosis