摘要
目的探讨婴幼儿细菌性肺炎血清抗体及补体检测的意义,揭示婴幼儿细菌性肺炎的病理生理机制。方法以婴幼儿细菌性肺炎病例为研究对象(肺炎组),选择同期来院体检的健康婴幼儿为对照组,入院后送检细菌性肺炎患儿的痰液进行培养,并测定两组受检儿的静脉血清抗体IgA、IgG、IgM及补体C3、C4的水平。结果 47例细菌性肺炎患儿培养出细菌50株,其中革兰阴性杆菌29株,革兰阳性球菌16株,其他细菌5株。肺炎组IgA水平较对照组明显降低,差异有统计学意义(P<0.05);肺炎组C3水平较对照组明显降低,差异有统计学意义(P<0.05)。结论机体的体液免疫及补体系统功能紊乱与婴幼儿细菌性肺炎密切相关。
Objective To investigate the significance of detection of serum antibodies and complement in infants with bacterial pneumonia（BP） to reveal its pathophysiological mechanism.Methods BP infants were chosen as study group,healthy infants as control group.Sputum culture was made in study group after admission.The levels of venous serum antibodies（IgA,IgG,IgM） and complement C3,C4 were determined in 2 groups.Results Fifty strains of bacteria were cultured in 47 BP infants,including 29 strains of Gram-negative,16 Gram-positive,5 others.IgA levels were significantly lower in study group than in control（P0.05）,and C3 levels lower（P0.05）.Conclusion Disorders of humoral immunity and complement system function are closely related to infant BP.
出处
《中国全科医学》
CAS
CSCD
北大核心
2011年第5期540-541,共2页
Chinese General Practice
关键词
肺炎
细菌性
抗体
补体
Pneumonia
bacterial
Antibodes
Complement
