期刊文献+

HER-2过表达乳腺癌治疗研究进展 被引量:7

The Progressive Study of HER-2 Overexpression in Breast Cancer
下载PDF
导出
摘要 HER-2基因成为近年来乳腺癌研究热点,它是一种与乳腺癌相关的癌基因,与乳腺癌的发生、发展及转移有密切关系,HER-2目前被认为是新的判断乳腺癌预后的独立指标。在治疗方面,Herceptin作为一种以癌基因为靶的治疗方式,使HER-2阳性的乳腺癌转移患者受益匪浅,近年来,中医中药凭借其特有优势在HER-2过表达乳腺癌的治疗中发挥作用。 HER-2 gene in breast cancer research in recent years become a hot spot,it is a cancer-related genes and breast cancer,and breast cancer development and metastasis are closely related,HER-2 is now considered the new Primary Breast Cancer independent indicators.In the treatment,Herceptin as a target gene in cancer treatment,so that HER-2 positive breast cancer patients benefited in recent years,Chinese medicine,with its unique advantages in the HER-2 overexpressing breast cancer treatment play a role.
出处 《中华中医药学刊》 CAS 2011年第3期560-562,共3页 Chinese Archives of Traditional Chinese Medicine
基金 上海市科技创新团队课题项目(1038) 第四批全国老中医药专家学术经验继承项目(30908)
关键词 乳腺癌 HER-2 HERCEPTIN 中医药 Breast Cancer HER-2 Herceptin Traditional Chinese Medicine
  • 相关文献

参考文献20

  • 1周雪瑞,黄选东.乳腺与乳腺癌[J].生物学通报,2004,39(7):26-27. 被引量:18
  • 2Demonty G, Bernard - Marry C, Puglisi F, et al. Progress and new standards of care in the management of HER - 2 positive breast cancer[ J ]. Eur J Cancer,2007, 43:497 -509. 被引量:1
  • 3Strauss B. Best hope or last hope access t o phase Ⅲ clini2cal trials of HER - 2/neu for advanced stage breast cancer patients[J]. J Advanced Nursing, 2000, 31:259 - 266 .. 被引量:1
  • 4Slamon DF, Clark GM, Wong SG, et al. Human breart cancer: correlation of relapse and surcival withe amplification of the her - 2/ncu ncogcne[ J ]. Science, 1987,235 ( 1785 ) : 177 - 182. 被引量:1
  • 5于斌,余小平,易龙,常徽,陈春烨,金鑫,糜漫天.黑米花青素对HER-2/neu高表达人乳腺癌细胞株MDA-MB-453移植瘤血管生成的影响[J].第三军医大学学报,2009,31(22):2206-2209. 被引量:9
  • 6Slamon DJ, Godolphin W, Jones LA, et al. Studies of the HER -2/neu proto - oneogene in human breast and ovarian cancer [J]. Science,1989,244:707 12. 被引量:1
  • 7Wolff AC, Hammond EH, Schwartz JN, et al. American Scciety of Clinical Oncology/College of American Pathologists guide line recommendations for human epidermal growth factor receptor teating in breast cancer[J]. Clin Oncol ,2007,25:118 45. 被引量:1
  • 8Ross J S, Fletcher J A. The HER -2/neu oncogene in breast cancer: prognostic factor, predictive factor and target for therapy [ J ]. Stem Cells, 1998, 16:413 428. 被引量:1
  • 9Brower F T, Ahmed S, Tamer P, et al. Prognostic variables in invasive breast cancer, contribution of comedo versus non comedoinsitu component [ J ]. Ann Surg Onco1,1995, 2: 440-444. 被引量:1
  • 10Chong D, Cooke T G, Reeves J R, et al. Quantitation of EGFR and eerbB -2 expression in preinvasive compared to invasive breast cancer[ J ]. EurJ Cancer, 1999, 35 (14) :203. 被引量:1

二级参考文献37

  • 1王庆,郭红辉,张名位,夏效东,邓斌,夏敏,凌文华.高效液相色谱法分析黑米皮花青素及其体内代谢产物[J].食品科学,2006,27(5):212-215. 被引量:20
  • 2张名位,张瑞芬,郭宝江,池建伟,魏振承,徐志宏.黑米花色苷对血管内皮细胞过氧化损伤的保护作用[J].营养学报,2006,28(3):216-220. 被引量:30
  • 3Wang L S, Stoner G D. Anthocyanins and their role in cancer prevention[J]. Cancer Lett, 2008, 269(2): 281 -290. 被引量:1
  • 4Redondo P, Jimenez E, Perez A, et al. N-acctylcysteine downregulates vascular endothelial growth factor production by human keratinocytes in vitro[J]. Arch Dermatol Rcs, 2000, 292(12) : 621 -628. 被引量:1
  • 5Miura S, Matsuo Y, Kawamura A, et al. JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27 ( kipl ) and Ras/p21 ( wall ) pathways [ J ]. Atherosclerosis, 2005, 182 (2) : 267 - 275. 被引量:1
  • 6Lamy S, Ruiz M T, Wisniewski J, et al. A prostate secretory protein94-derived synthetic peptide PCK3145 inhibits VEGF signalling in endothelial cells: implication in tumor angiogenesis[ J]. Int J Cancer, 2005, 118(9) : 2350 -2358. 被引量:1
  • 7Grummer M A, Sullivan J A, Magness R R, et al Vascular endothelial growth factor acts through novel, pregnancy-enhanced receptor signalling pathways to stimulate endothelial nitric oxide synthase activity in uterine artery endothelial cells [ J ]. Biochem J, 2009, 417 (2) : 501 -511. 被引量:1
  • 8Lamy S, Blanchette M, Michaud-Levesque J, et al. Delphinidin, a dietary anthocyanidln, inhibits vascular endothelial growth factor receptor-2 phosphorylation [ J ]. Carcinogenesis, 2006, 27 (5) : 989 - 996. 被引量:1
  • 9Chen P N, Kuo W H, Chiang C L, et al. Black rice anthoeyanins inhibit cancer cells invasion via repressions of MMPs and u-PA expression[J]. Chem Biol Interact, 2006, 163(3) : 218 -229. 被引量:1
  • 10Lipton A. Ali S.M,Leitzel K. et al. Elevated serum her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin 0ncol,2002,20(6): 1467- 1472. 被引量:1

共引文献49

同被引文献84

引证文献7

二级引证文献58

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部