摘要
从本草记载开始阐述了龙胆药材4种基源植物中质量最优的条叶龙胆资源的变化。条叶龙胆野生资源的开发是按由南到北的顺序进行的。我国东北地区条叶龙胆的开发较晚,但由于龙胆的生物学特性及草原破坏等多种原因,在几十年的时间内野生资源便遭到了严重破坏。目前野生资源接近枯竭,栽培严重滞后,致使这一优质龙胆药材市场占有率不断降低。条叶龙胆的可持续发展必须以栽培为主,而育种、栽培技术等与高产密切相关的措施的优化与推广等问题急需解决。
Objective： To investigate the chemical constituents of the whole herb of Scutellaria barbata D. Don. Methods： The compounds were isolated by silica gel column chromatography and purified by Sephadex LH-20 column chromatography and recrystallization. The structures were elucidated on the basis of physicochemical properties and spectroscopic analyses. Results： Nine compounds were separated and identified as：β-sitosterol（ 1 ）,5-hydroxy-7, 4＇-dimethoxyflavone （ 2 ）, 5-hydroxy-7, 8,4＇-trimethoxyflavone （ 3 ）, 5-hydroxy-6, 7,4＇-trimethoxyflavone, salvigenin （4）, 5,7-dihydroxy-8-methoxyflavone （ wogonin, 5 ）, 2-hydroxy-3-methylanthraquinone （ 6 ）, （ E ） -3- （ 4-hydroxyphenyl ） acrylic acid ethyl ester（ 7 ） ; ethyl-4-hydroxybenzoate （ 8 ） ,p-hydroxybenzaldehyde （ 9 ）. Conclusion： compounds 2,3, 6,7 were isolated from the genus Scutellaria for the first time, and compound 4 was obtained from S. barbara.
出处
《中国现代中药》
CAS
2011年第2期10-12,28,共4页
Modern Chinese Medicine
基金
国家科技基础性工作专项重点项目--珍稀濒危和大宗常用药用植物资源调查(2007FY110600)
关键词
条叶龙胆
历史沿革
资源
栽培
Lamiaceae
Scutellaria
Scutellaria barbata
Chemical constituents
