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乳腺恶性腺肌上皮瘤一例及文献复习 被引量:1

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摘要 目的探讨乳腺恶性腺肌上皮瘤的临床病理特征和鉴别诊断。方法对1例乳腺恶性腺肌上皮瘤进行光镜观察及免疫组织化学检测,并结合临床及病理特点进行分析。结果肿瘤发生于乳腺外上象限,不规则形,与周围界限不清,切面灰黄色。临床上主要表现为乳腺无痛性包块,活动度差。其组织学特点为肿瘤呈浸润性生长,由腺上皮和肌上皮两种细胞组成,呈巢状、腺管状,中间为腺上皮,周围为肌上皮,肌上皮细胞有明显的异型性,核分裂增多,可见坏死。免疫组织化学,腺上皮细胞表达EMA和CK(34BE12),肌上皮细胞表达p63、SMA和Calponin。结论乳腺恶性腺肌上皮瘤是一种罕见的乳腺恶性肿瘤,具有一定的病理学特征,有转移者预后差,其诊断与鉴别诊断有赖于组织病理学及免疫组织化学检测。
出处 《肿瘤研究与临床》 CAS 2011年第2期132-134,共3页 Cancer Research and Clinic
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