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脂联素、血脂、SOD与代谢综合征痰湿内蕴辨证关系研究 被引量:6

Relation of Adiponectin,Blood lipid and SOD with Metabolic Syndrome due to Phlegm-dampness Accumulation
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摘要 目的:研究代谢综合征患者痰湿内蕴辨证与血清脂联素、血脂、SOD之间的关系,为中医辨证代谢综合征寻找客观依据以便更好地指导临床治疗。方法:共收集代谢综合征患者49例,辨证分为痰湿内蕴型25例,非痰湿内蕴型24例;另设20例我院门诊健康体检者为对照组。测量患者的血清脂联素、血脂、SOD,分析脂联素、血脂、SOD与痰湿内蕴辨证之间的关系。结果:2组代谢综合征患者的血清脂联素和超氧化物歧化酶低于对照组,差异有统计学意义。代谢综合征患者2组比较,痰湿内蕴组脂联素水平低于非痰湿内蕴组,2组SOD水平无明显差异。结论:代谢综合征患者存在低脂联素血症,代谢综合征患者痰湿内蕴辨证与脂联素有直接相应关系,脂联素水平可作为辨证代谢综合征的客观指标及疗效参考依据。 Objective:To investigate how metabolic syndrome due to phlegm-dampness accumulation is related to adiponectin,superoxide dismutase(SOD),and blood lipid,aiming to find out objective evidences in support of differentiation of metabolic syndrome and better guide clinical treatment.Methods:Forty-nine patients with metabolic syndrome were differentiated as phlegm-dampness accumulation (n=25) and non-accumulation (n=24),compared with 20 healthy persons. Levels of adiponectin,SOD,blood fat were detected respectively. Results:Levels of adiponectin and SOD were significantly lower in metabolic syndrome patients than in the healthy population. Adiponectin level was lower in the accumulation group than in the non-accumulation group. Conclusion:Metabolic syndrome patients presented low level of adiponectin. Adiponectin is closely related to the syndrome of phlegm-dampness accumulation,thus could be an objective evidence for syndrome differentiation and efficacy evaluation.
出处 《世界中医药》 CAS 2011年第1期73-75,共3页 World Chinese Medicine
基金 深圳市科技计划资助项目(200404122)
关键词 代谢综合征 脂联素 血脂 SOD 痰湿内蕴 Metabolic syndrome Adiponectin Blood lipid SOD Phlegm-dampness accumulation
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