摘要
以三聚氯氰为初始原料,以丙酮为溶剂,先于-5℃下通入氨气,生成2-氨基-4,6-二氯-1,3,5-三嗪,再在-10℃下与二甲胺水溶液反应生成2-氨基-4-二甲氨基-6-氯-1,3,5-三嗪,用乙醇重结晶,最后同三氟乙醇在金属钠存在下回流反应生成产物,用乙醇和水混合溶剂重结晶得到含量99%以上的2-氨基-4-二甲氨基-6-三氟乙氧基-1,3,5-三嗪。
Using cyanuric chloride as starting material, acetone as the solvent, first under -5℃, ammonia is passed to produce 2-amino-4,6-dichloro-1,3 ,5-triazine, and then under -10℃a reaction was conducted with dimethylamine aqueous solution to produce 2-amino-4-dimethylamino-6-chloro-1,3 ,5-triazine, recrystallized with ethanol, and finally a reaction was finished with trifluoroethanol in the presence of sodium to produce final product. The final product is recrystallized with ethanol and water, more than 99% content of 2-amino-4-dimethylamino-6- trifluoroethoxy-1,3,5-triazine is obtained.
出处
《精细与专用化学品》
CAS
2011年第2期25-26,共2页
Fine and Specialty Chemicals
