摘要
目的:运用参芪扶正注射液配合化疗,观察化疗患者骨髓抑制、消化道反应、KPS评分变化。方法:将符合纳入标准的肺癌化疗病人100例,应用信封法随机分组,实验组应用PD方案化疗,同时配合使用参芪扶正注射液;对照组单纯应用PD方案化疗。观察参芪扶正注射液对化疗所致的骨髓抑制、消化道反应、KPS体力状况评分的影响。结果:实验组WBC,NEU降低程度明显小于对照组(P<0.05);实验组恶心、腹泻症状明显轻于对照组(P<0.05);实验组KPS体力状况评分降低程度极明显小于对照组(P<0.01)。结论:参芪扶正注射液能减轻化疗后血WBC、NEU的下降程度,减轻化疗引起的恶心、腹泻症状,改善化疗后患者的KPS体力状况评分。
Objective：The influence of the Shenqi Fuzheng injection to the patients who got the injection to go with the chemotherapy in hematology change,digestive response,the KPS grades along and after chemotherapy.Method：One-hundred patients were selected according to the standard of the lung cancer chemotherapy.With the quantization random controlled method,we devided the patients into two groups.The treatment group patients re-ceived the administration of Shenqi Fuzheng injection and、PD chemotherapy.The control group patients received only PD chemotherapy.We observed the influence of Shenqi Fuzheng injection on the aspects of myelosuppression,the response to chemotherapy in gastrointestinal and the KPS.Result：The reduce of the white blood cell（WBC）,the neutrophilic granulocyte（NEU） in the treatment group were lower than the control group obviously（P 〈 0.05）;The response to chemotherapy in gastrointestinal of the treatment group was lighter than the control group（P 〈 0.05）;The reduce of KPS were lower than the control group obviously（P 〈 0.01）.Conclusion：Shenqi Fuzheng in-jection can reduce the decrease of WBC,NEU after the chemotherapy,Shenqi Fuzheng injection can reduce the chemotherapy-induced nausea and diarrhea,Shenqi Fuzheng injection can improve the patient ’s KPS physical strength condition
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第5期231-232,共2页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
肺癌
参芪扶正注射液
化疗
lung cancer
Shenqi Fuzheng injection
chemotherapy
