摘要
目的观察慢性脑供血不足(chronic cerebral circulation insufficiency,CCCI)患者认知状况,为临床治疗提供依据。方法选择56例CCCI(观察组)及同期健康体检者44例(对照组),观察组予尼莫地平、阿司匹林肠溶片、辛伐他汀滴丸口服。观察组于治疗前和治疗5个月后行认知功能评定,包括行简易智能状况量表(MMSE),画钟表测试(CDT)评定。对照组与观察组治疗前同期行MMSE、CDT评定。结果观察组治疗后MMSE、CDT评分均升高,与治疗前比较差异有统计学意义(P<0.01),但观察组治疗前后MMSE、CDT评分均低于对照组,差异均有统计学意义(P<0.01)。结论 CCCI患者认知功能经系统治疗有所改善,是否能延缓疾病发展有待长期观察。
Objective To observe cognitive function in patients with chronic cerebral circulation insufficiency （CCCI） for clinical therapy. Methods 56 patients with CCCI （ observation group） and 44 healthy people who underwent physical examination（ control group） at the same period were selected. The observation group was given oral nimodipine, aspirin enteric-coated tablets and simvastatin. Before treatment and 5 months after treatment, the cognitive evaluation including the Mini Mental Status Scale （ MMSE）, Clock Drawing Test （CDT） assessment were carried out and both the groups received concomitant MMSE and CDT assessment before treatment. Results MMSE, CDT scores in observation group were higher when compared with that before treatment, and the difference was statistically significant （ P 〈 0. 01）, but it was lower even before or after treatment in observation group when compared with that in control group, and the differences were statistically significant （P 〈 0. 01 ） ： Conclusion The cognitive function in patients with CCCI can improve after systemic treatment, but long time observation is needed to determine whether dementia can be delayed or not.
出处
《临床误诊误治》
2011年第2期44-45,共2页
Clinical Misdiagnosis & Mistherapy
关键词
椎底动脉供血不足
认知
智能状况量表
画钟表测试
Vertebral artery circulation insufficiency
Cognition
Mental status scale
Clock drawing test
