摘要
恶性肿瘤肾损害肾脏病理及临床表现多种多样。其肾损害的病理类型几乎覆盖所有肾小球病理改变,实体肿瘤多呈现膜性肾病,霍奇金病常呈现微小病变。其肾损害的临床表现也几乎覆盖所有肾损害的临床类型,但以肾病综合征最为常见。肾损害可早于原发恶性肿瘤的发现。因此,肾脏病理医生及临床医生应高度警惕恶性肿瘤肾损害的病理和临床蛛丝马迹,特别是对中老年患者,以早期甄别恶性肿瘤,合理治疗,改善患者预后。
Summary:Malignancy-associated kidney damage is a common complication of neoplastic disease with char- acteristic clinical features and pathologic alterations. Pathologic examinations exhibit a wide range of glomerular pathological changes. Solid tumors are usually associated with membranous nephropathy, whereas Hodgkin's lym- phomas are associated with minimal pathological changes. Clinic manifestations exhibit diversity and nephrotic syn- drome is the most common presentation. Renal lesions could act as the initial manifestation and be manifested clin- ically before tumor detection. In conclusion, nephrologists and pathologists shonld be alerted to discriminate malignancy-associated kidney damages,especially in elderly patients.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第2期100-102,共3页
Chinese Journal of Practical Internal Medicine
关键词
恶性肿瘤
肾损害
膜性肾病
肾病综合征
malignancy
kidney damage
membranous nephrotic
nephritic syndrome