摘要
促红细胞生成素(EPO)主要由肾脏产生,其作用为调节红细胞生成。EPO缺乏可致贫血,重组促红细胞生成素(rHuEPO)治疗慢性肾衰引起的贫血疗效确切且不良反应小。本文综述EPO的生理功能、临床应用及新品种开发。
Erythropoietin (EPO) produced by the kidney in adults is a kind of glycoprotein hormone, which regulates red cell production. Lacking of EPO anemia. Treatment with recombinant human EPO (rHuEPO) is an effective and safe approach to improve anemia associated with chronic renal failure (CRF). This review summarizes the physiological function, clinical application and development of EPO.
出处
《世界临床药物》
CAS
2011年第2期88-92,共5页
World Clinical Drug