摘要
目的:以苯酚为原料,经酯化、Fries重排、烷基化、Vislsmeier反应等,合成3-氯-3-(4-苄氧基)-3-苯丙烯醛。方法:查阅、分析、归纳相关文献,设计出3-氯-3-(4-苄氧基)-3-苯丙烯的合成路线,运用化学合成法合成该目标产物,并检测其纯度。结果:通过实验研究,合成了-3-氯-3-(4-苄氧基)-3-苯丙烯醛。结论:3-氯-3-(4-苄氧基)-3-苯丙烯醛的熔点为88～90℃,收率76.9%,纯度98.21%。
Objective： 3-chloro-（4-benzyloxy）-3-benzene propylene aldehyde was synthesized from phenol and acetic anhydride by esterification,Fries rearrangement and Vislsmeier reaction.Methods： Basing on relative literatures,a method of synthesizing 3-chloro-（4-benzyloxy）-3-benzene propylene aldehyde was established and its purity was measured.Results： 3-chloro-（4-benzyloxy）-3-benzene propylene aldehyde was synthesized successfully.Conclusion： The yield of this new chemical was 76.9%,and its melting point 88-90 ℃ and purity was 98.21%.
基金
大理学院青年科学基金资助项目(2008X59)
