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ATP敏感性钾通道在心血管疾病中的作用 被引量:3

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摘要 1983年日本学者在豚鼠心室肌细胞上发现了一类非电压依赖、受细胞内三磷腺苷(ATP)和二磷腺苷(ADP)调节的选择性钾通道,命名为ATP敏感性钾通道(KATPchannel)。KATPchannel分为细胞膜、线粒体、核膜KATPchannel三类,在心血管疾病如急性心肌缺血、缺血预适应、心律失常、高血压等中发挥的作用十分广泛,但何种KATPchannel起关键作用还有一定争议,深入研究KATPchannel在心血管系统中的作用对于防治心血管疾病具有重要意义。
出处 《新医学》 2010年第12期821-824,共4页 Journal of New Medicine
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