摘要
目的探讨门静脉高压（主要指肝硬化引起）性胃病（PHG）与幽门螺杆菌（Hp）感染的关系。方法选36例PHG患者和50例慢性胃炎患者进行胃镜和Hp检测分析。结果门脉高压性胃病患者组的Hp感染率为23．07％。慢性胃炎组的Hp感染率为25．0％，两者差异无显著性（P〉0．05）。门脉高压患者轻重度之间Hp感染率分别为23．81％和20．0％。差异无显著性（P〉0．05）；门脉高压患者Hp感染率23．60％显著低于慢性胃炎组72．10％（P〈0．01）；门脉高压患者慢性活动性胃炎的发生与Hp感染密切相关，活动性胃炎Hp感染率53．84％比非活动性胃炎Hp感染率16．66％显著升高（P〈0．01）。结论PHG的Hp感染率降低可能与肝硬化患者胃内环境不适合Hp生存有关。PHG患者胃黏膜的活动性炎症，可能由幽门螺杆菌感染引起，与门静脉高压关系不大。
Objective To investigate the relationship of portal hypertensive gastropathy （PHG） associated Helicobacter pylori （H.pylori） infection. Methods Gastroscopy was performed in 36 patients with cirrhosis divided into PHG and non PHG, and H.pylori was detected.The comparison was made with 50 patients with chronic gastritis. Results There was no difference in the infection rate of H.pylori between cirrhosis patients with PHG and without PHG （P〉0.05） .The same result was found in the patients of different degree of PHG. The infection rate of H.pylori in portal hypertensive patients was lower than in group of chronic gastritis （P〈0.01） . Conclusion The infection rate of H.pylori in the cirrhotic patients with PHG is declind, the possible cause may be that circumstance of stomch with cirrhosis is not fit for H.pylori .The active inflammation of PHG may result from theinfections of H.pylori.
关键词
门静脉高压性胃病
幽门螺杆菌
慢性胃炎
Portal hypertensive gastropathy （PHG）： Helicobacterpylori （H.pylori）： Chronic gastritis.
