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硼替佐米联合地塞米松治疗多发性骨髓瘤合并肾功能不全失代偿期的疗效观察 被引量:4

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摘要 多发性骨髓瘤(multiple myeloma,MM)是一种起源于B细胞系的浆细胞恶性克隆增殖性疾病,特征为异常浆细胞增多,产生单克隆免疫球蛋白,并在骨髓内恶性增殖,引起骨折和骨髓功能衰竭,产生临床症状。如果不进行治疗,进展期患者的中位生存期仅为6个月,接受传统化疗,中位生存期也不超过3年,仅有25%的患者可以生存5年以上,所以MM一直被认为是一种不可治愈的疾病。
出处 《中国药物与临床》 CAS 2011年第1期80-81,共2页 Chinese Remedies & Clinics
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参考文献8

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二级参考文献5

  • 1Gregersen H, Ibsen JS, Nielsen M. Renal insufficiency in myelomatosis. Prognostic factors and survival. Ugeskr Laeger,1997 ,159:3387-3392. 被引量:1
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