摘要
目的提高对以风湿病症状为突出表现的血液系统肿瘤的认识，以减少该类疾病的漏诊。方法总结15例以风湿病症状为突出表现，拟诊风湿性疾病，但最终确诊为血液系统肿瘤患者的临床资料，分析其临床表现。结果15例患者中，有多种风湿病表现，发热占66.7％（10／15），皮疹占40％（6／15），关节炎占20％（3／15），拟诊风湿病中以血管炎居多[6例（40％）]，成年人斯蒂尔（Still）病3例，淀粉样变、皮肌炎、风湿性多肌痛、脂膜炎各1例，未分类2例。所患血液系统肿瘤中以淋巴瘤居多[9例（60％）]，白血病3例，多发性骨髓瘤3例。结论血液系统肿瘤可出现风湿病表现，对于风湿病难以解释的临床表现、常规治疗效果差者，要警惕血液系统肿瘤的可能。
Objective To strengthen the awareness that hematological tumors preseht with certain rheumatic symptoms for early diagnosis and treatment to a hidden neoplasm. Methods 15 patients admitted to rheumatic ward with suspected rheumatic disease were finally diagnosed as hematological tumors. Their rheumatic manifestations and occult malignancies were collected. Results A variety of rheumatic manifestations were presented. Among 15 patients, 10（66.7 %） had fever, 6 （40 %） skin lesion, 3（20 %） arthritis, 6（40 %） vasculitis, 3 adult onset of Still＇s disease, 2 unclassified, and one of the each following disease： amyloidosis, dermatomyositis, polymyalgia rheumatica, and panniculitis. 9 of lymphoma, 3 leukemia, 3 multiple myeloma were finally diagnosed. Conclusion Rheumatic disorders associated with hematological tumors include a variety of conditions. An extensive investigation for occult malignancies with some rheumatic symptoms is recommended when accompanied by specific findings of suggestive malignancy.
出处
《白血病．淋巴瘤》
CAS
2008年第4期287-288,290,共3页
Journal of Leukemia & Lymphoma
关键词
血液肿瘤
风湿性疾病
Hematologic neoplasms
Rheumatic diseases
