摘要
目的 分析Rh血型系统中不规则抗体的临床意义。方法对1例带有抗-Ce联合抗体的患者,采用盐水法鉴定血型,并进行直接抗球蛋白试验,抗球蛋白法进行抗体鉴定和效价测定,吸收放散试验鉴定联合抗体,盐水法、抗球蛋白法和聚凝胺法进行配血。结果根据该例有抗-Ce联合抗体患者血清学抗体检测结果,为其找到了配合的血液,输注后无不良反应,治疗效果良好。结论对于经常需要输血的患者或还未生育的女性,在输血前除了做必要的抗体筛查和鉴定其相配合的血液外,建议作RhD以外的各因子的检测,做到Rh系统的配合性输注,避免此系统不规则抗体的产生,保证临床输血的安全。
Objective To analyze the clinical significance of irregular antibodies in Rh blood group system.Methods A patient carrying anti-Ce combined antibody was subjected to blood grouping by saline method as well as direct antiglobulin test,then determined for antibody potency by antiglobulin test and for combined antibody by absorption elution test,based on which blood matching was performed by saline method,antiglobulin method and polybrene method.Results The serum antibody of the said patient was identified,based on which blood matching was successfully performed.No adverse reaction was observed after blood transfusion,and the curative effect was satisfactory.Conclusion Besides the routine antibody screening and blood matching,it is recommended to determine various factor other than RhD for the patients needing regular blood transfusion and the women without history of giving birth to ensure the compatible transfusion of Rh system and avoid the irregular antibodies so as to ensure the safety of clinical blood transfusion.
出处
《中国生物制品学杂志》
CAS
CSCD
2011年第1期88-90,共3页
Chinese Journal of Biologicals
关键词
血型鉴定和交叉配血
抗体筛查
不规则抗体
输血反应
Rh因子
Blood grouping and cross matching
Antibody screening
Irregular antibody
Transfusion reaction
Rh factor
