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脑外伤患者认知障碍与损伤部位的相关性研究 被引量:25

Study of the Correlation between Cognitive Impairment and Locus of the Mild to Moderate Cerebral Injury
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摘要 目的:探讨轻中型脑外伤部位与认知功能障碍的关系,了解不同部位损伤所致的认知功能障碍的特点。方法:采用中文版蒙特利尔认知评估量表(MoCA)评估脑外伤后有认知障碍的患者120例,将其脑部损害的CT或MRI定位与MOCA的7个分项目(定向力ORT、视空间与执行功能EF、命名NAM、记忆MEM、注意ATT、语言功能包括复述与流畅性LANG、抽象概括ABS)的测试结果进行相关分析。结果:认知功能障碍与左、右侧没有相关性(P>0.05);额叶损害与ORT、EF、MEM相关(P<0.05);颞叶损害与EF、MEM、LANG相关(P<0.05);顶叶损害与EF、NAM、MEM、ATT相关(P<0.05);基底节区损害与EF、MEN、LANG相关(P<0.05);小脑、枕叶损伤与认知功能障碍的发生无相关(P>0.05)。结论:轻中型脑外伤患者认知功能障碍与损伤的部位有关,以额叶、颞叶、顶叶损伤为明显;MoCA对于轻中度脑外伤患者认知功能受损有较高的检出率。 Objective: To study the correlation between cognitive impairment and locus of the mild to moderate cerebral injury and to observe the characters of cognitive impairment with cerebral injury of different locus.Method: Cognitive function was tested with Montreal cognitive assessment(MoCA) in 120 patients with cerebral injury.Correlation between the locus of cerebral injury and cognitive impairment was analyzed with 7 items(ORI,EF、NAM、MEM、ATT、LANG、ABS)of MoCA.Result: The lesions of either side of brain were no correlation(P0.05).The frontal lobe was related to ORT,EF,and MEM(P0.05),and the parietal lobe was related to EF,NAN,MEM and ATT(P0.05).The temporal lobe was related to EF,MEM and LANG(P0.05),and the basilar lesion was related to EF,MEN and LANG(P0.05).The occipital lobe and cerebellar were both not related to cognitive impairment(P0.05).Conclusion: Cognitive dysfunction is related to the locus of brain lesion in the patients with mild to moderate traumatic brain injury,and this is especially true for lesions in the frontal,temporal and parietal lobes.We have a higher detection rate using in MoCA on the mild to moderate cognitive dysfunction in patients with traumatic brain injury.
出处 《河北医学》 CAS 2011年第1期20-23,共4页 Hebei Medicine
关键词 脑外伤 认知障碍 MOCA Traumatic brain injury Cognitive dysfunction MoCA
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