摘要
目的探讨脑卒中部位与认知功能障碍之间的关系,观察不同部位脑卒中所致认知功能障碍的特点。方法采用中文版蒙特利尔认知评估量表(MOCA)对100例脑卒中患者进行测试,将脑卒中患者的CT/MRI定位与MOCA的7个分项目(定向力ORT、视空间与执行功能EF、命名NAM、记忆MEM、注意ATT、语言功能包括复述与流畅性LANG、抽象概括ABS)的测试结果进行相关分析。结果(1)100例患者中脑梗死63例,脑出血37例,其中额叶卒中15例,顶叶15例,颞叶12例,枕叶8例,丘脑14例,基底节20例,小脑8例,脑桥8例。额叶、顶叶、颞叶、枕叶、丘脑、基底节卒中与认知功能障碍发生相关(P<0.05)。枕叶、脑桥卒中与认知功能障碍无关(P>0.05)。(2)额叶卒中患者认知功能的EF、ORT、MEM、ATT、ABS损害明显;顶叶卒中与认知功能的NAM、MEM、ATT、EF损害有关;颞叶卒中与LANG和EF损害有关,枕叶卒中患者视空间及执行功能(EF)损害明显;丘脑损害语言功能(LANG)受损明显;基底节卒中患者MOCA各分测验均有损害。结论脑卒中患者认知功能障碍的发生与卒中部位有关,不同部位卒中损害认知功能不同。
Objective To study the correlation between cognitive impairment and locus of cerebral stroke and to observe the characters of cognitive impairment with cerebral stroke of diferrent locus. Methods Cognitive function was tested with Montreal cognitive Assessment（MOCA） in 100 patients with stroke. Correlation between the locus of stroke and cognitive impairment was analyzed with 7 items （ ORI , EF,NAM,MEM,ATT,LANG,ABS） of MOCA. Results （1） 100 stroke patients were includes 63 cerebral infarction and 37 cerebral hemorrhage. Stroke of frontal lobe, temporal lobe, parietal lobe, occipital lobe, thalamus and basal nucleous led to obvious cognitive impairment （P 〈 0.05 ） while-stroke of cerebellum and pons didnt lead to cognitive impairment（ P 〉 0.05 ）. （2） Stroke of frontal lobe impaired EF, ORT, MEM ,ATT and ABS, stroke of parietal lobe impaired NAM, MEM ,ATT,EF, sroke of occipital lobeimpaired EF;stroke of thalamus impaired LANG;almost all items of MOCA were impaired in basal nucleous stroke. Conclusion Cognitive impairment is related to the locus of cerebral stroke.
出处
《临床合理用药杂志》
2009年第9期1-3,共3页
Chinese Journal of Clinical Rational Drug Use
