摘要
目的观察芬舒雅（Ｆａｎｃｉａ）吸入治疗改善微循环障碍的即刻效应及协同效应。方法６０例心脑血管疾病患者进行治疗前后甲襞微循环对比检测与分组比较，用田牛加权积分法评定。结果１治疗后微循环各项积分值改善迅速、显著，尤以血流速度、血管充盈度及毛细血管管径改善更显著（均Ｐ<０.００１～０.０１）；２芬舒雅单独治疗组（２２例）与芬舒雅联合治疗组（３８例）、高血压组（１１例）与高血压合并冠心病组（１４例）及心脑血管病组（４２例）与非心脑血管病组（１８例）组间比较，疗效无显著差异（均Ｐ＞０．０５）。结论芬舒雅改善微循环疗效确切，即刻效应明显，其作用无特异性，与其他增强心血管功能药物有协同效应，可作为防治心脑血管病的药物及非心脑血管疾病的辅助治疗药物。
Objective To study the immediate effect and co-effect of Fancia (inhalant) on improving microcirculation disturbance and criteria for evaluation of the therapy. Methods 60 patients with cardio-cerebro-vascular diseases divided into four groups were observed by microcirculation of nailfold (MN) before and after treatment with Fancia using Cochran's Test Multiple Quantitative Evaluation Method(MQEM) as an evaluation index. Results After treatment with Fancia,the score value of morphology, hemodynamics and the nailfold microcirculation as a whole were significantly decreased (0. 8967±0. 7195-0. 7517±0. 7041, 0. 5867±0. 3842-0. 4567±0. 7817, 2. 4933±2. 2846-1. 8533± 1. 0817,P<0. 001 ), especially the capillary loop diameter, the capillary density, the velocity of blood flow and RBC aggregation remarkably improved. There was no significant difference between the pureFancia group and co-Fancia treatmernt group or simple hypertension group and the hypertention with coronary disease group or the cerebro-cardio-vascular diseaase group and non-cerebro-cardio-vascular disease group before and aftert treatment.Conclusion it is suggested that Fancia(inhalant) has a distinet and immediate effect on improving microcirculation,but its effect is not specific. Fancia may be used as a symptomatic therapy for cardio-vascular disease and an aid for non-cardio-vascular disease.
出处
《中国微循环》
1999年第3期181-183,共3页
Journal of Chinese Microcirculation
关键词
芬舒雅
甲襞微循环
心脑血管疾病
Fancia(inhalant) Microcirculation of Nailfold (MN) Calidio-cerebro-vascular disease
