摘要
组织因子（tissue factor，TF）是一种广泛存在于多种组织细胞浆膜上的糖蛋白，是凝血级联的主要始动因子，在外源性凝血途径中起着关键性的作用。而组织因子途径抑制物（tissue factor pathway inhibitor。TFPI）是迄今为止发现的外源性凝血途径的唯一特异性生理抑制物，能阻止血栓形成。
出处
《实用医学杂志》
CAS
北大核心
2011年第2期321-323,共3页
The Journal of Practical Medicine
参考文献19
-
1Crawley J, Andrew F, Westmuekett D, et al. Expression,localization,and activity of tissue factor pathway inhibitor in normal and atheroselerotie human vessels [J].Arteioscler Thromb Vase Boil, 2000,20(5) : 1362-1373. 被引量：1
-
2Bajaj M S, Tyson D R, Sarah A, et al. Role of GATA motif in tissue factor pathway inhibitor gene expression in malignant cells [J]. Thromb Res, 2001,101 (3) :203-211. 被引量：1
-
3Steppich B,Mattisek C,Sobozyk D,et al. Tissue factor pathway inhibitor on circulating microparticles in acute myocardial infarction [ J ]. Thromb Haemost, 2005,93 ( 1 ) : 35-39. 被引量：1
-
4Levi M, Keller Tr, van Gorp E, et al. Infection and inflammation and the coaglllation system [J]. Cardiovase Res, 2003,60( 1 ) : 26-39. 被引量：1
-
5Maly M, Vojacek J, Hrubos V, et al. Tisue factor, tissue factor pathway inhibi-tor and cytoadhesive molecules in patients with an acute corollary syndrome [J]. Physiol Res, 2003,52 (6):719-728. 被引量：1
-
6时辉宁,钟玉绪,丁日高,廖明阳.组织因子途径抑制物-2的结构及其生物学作用研究进展[J].中国医药生物技术,2009,4(3):233-235. 被引量：2
-
7Zaman A G, Helft G, Worthley S G, et al. The role of plaque rupture and thrombosis in coronary artery disease [J]. Atherosclerosis, 2000,149(2) : 251-266. 被引量：1
-
8Banai S, Gertz S D. Tissue factor as therapeutic target in coronary syndromes [J]. Am J Cardiol, 2001, 87(6) :763-765. 被引量：1
-
9Moons A H, Levi M, Peters R J. Tissue factor and coronary artery disease [J]. Cardiovasc Res, 2002,53 (2) :313-325. 被引量：1
-
10Ardissino D, Merlini P A, Arlens R, et al. Tissue factor in human coronary atherosclerotic plaques [ J ]. Clin Chim Acta, 2000,219 (2) : 235-240. 被引量：1
二级参考文献25
-
1顾俊,王长谦.基质金属蛋白酶与冠脉再狭窄[J].心脏杂志,2005,17(1):77-80. 被引量：5
-
2Chenqi ZHANG,Desheng KONG,Xingang LIU,Xiaomin YAN,Linsen DAI,Duan MA.Spectroscopic Analysis on the Effect of Temperature on Kunitz Domain 1 of Human Tissue Factor Pathway Inhibitor-2[J].Acta Biochimica et Biophysica Sinica,2007,39(6):406-412. 被引量：3
-
3Schecter A.D.,Giesen P.L.A.,et al.Tissue factor expression in human arterial smooth muscle cells.TF is present in three cellular pools after growth factor stimulation[ J].Journal of Clinical Investigations,100,2276-2285. 被引量：1
-
4Maly M,Vojacek J,Harbos V,et al.Tissue factor,tissue factor pathway inhibitor and cytoadhesive molecules in patients with an acute coronary syndrome[J].Physoil Res,2003,52(6):719 -728. 被引量：1
-
5Steppich B,Mattisek C,sobczyk D,et al.Tissue factor pathway inhibitor on circulating microparticles in acute myocardial infarction[ J ].Thromb Haemost,2005,93 (1):35-39. 被引量：1
-
6Ardissino D,Merlini PA,Arlens R,et al.Tissue factor antigen and activity in human coronary atherosclerotic plaques[J].Lancet,1997,349:769-771. 被引量：1
-
7Carter AM,Leatham EM,Math PMW,et al.Inflammation,thrombosis and acute coronary syndromes[ J ].Diab Vasc Dis Res,2005,2(3):113 -121. 被引量：1
-
8Steppich B,Mattisek C,Sobczyk D,et al.Tissue factor pathway inhibitor on circulating microparticles in acute myocardial infarction[ J ].Thromb Haemost,2005,93 (1):35-39. 被引量：1
-
9Falciani M,Gori AM,Fedi S,et al.Elevated tissue factor and tissue factor pathway inhibitor circulating levels in ischemic heart diseases patients[ J ].Thromb Haemost,1998,79:495-499. 被引量：1
-
10Soejima H,Ogawa H,Yause H,et al.Heightened tissue factor associated with tissue factor pathway inhibitor and prognosis in patients with unstable angina[ J ].Circulation,1999,(22):2908-2913. 被引量：1
共引文献5
-
1李丹.重组组织因子途经抑制物(rTFPI)预防血管成形术后再狭窄的实验研究[J].齐齐哈尔医学院学报,2006,27(1):13-14.
-
2陈桂英,王晓梅,周立君,黄明学,王也,原琳,张依娜.中国北方汉族人群TFPI-287T>C基因多态性与急性心肌梗死的关系研究[J].哈尔滨医科大学学报,2009,43(3):245-248. 被引量：1
-
3段超,陈鑫,邱志兵.血管外膜成纤维细胞与血管再狭窄[J].心脏杂志,2010,22(2):285-288. 被引量：1
-
4陆文彬,沈成兴.细胞因子在单核细胞致动脉硬化中的作用[J].心脏杂志,2011,23(2):266-269. 被引量：1
-
5石坚,王立新,任铂宇.尼古丁对血管内血栓形成的影响[J].中西医结合心脑血管病杂志,2011,9(12):1489-1490. 被引量：4
同被引文献26
-
1李中原,涂秀华.红花黄色素的药理研究进展[J].中药新药与临床药理,2005,16(2):153-156. 被引量：113
-
2管高峰,华先平,王琳,杜令,孔祥辉.丹红注射液对动脉粥样硬化家兔脂代谢及血管内皮功能的影响[J].临床心血管病杂志,2007,23(4):304-306. 被引量：107
-
3李亚里,杨怡卓.人乳头瘤病毒亚型检测在宫颈病变分流管理中的意义[J].中国实用妇科与产科杂志,2007,23(7):501-503. 被引量：55
-
4Patterson C, Stouffer GA, Madamanchi N, et al. New tricks for old dogs: nonthrombotic effects of thrombin in vessel wall biology[J]. Circ Res, 2001, 88(10): 987-997. 被引量：1
-
5Lindner V, Reidy MA. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor [J]. Proc Natl Acad Sci U S A, 1991, 88 (9): 3739-3743. 被引量：1
-
6Ferns GA, Avades TY. The mechanisms of coronary restenosis: insights from experimental models[J]. Int J Exp Pathol, 2000, 81 (2): 63-88. 被引量：1
-
7Wang L, Miller C, Swarthout RF, et al. Vascular smooth musclederived tissue factor is critical for arterial thrombosis after ferric chloride induced injury[J]. Blood, 2009, 113(3): 705-713. 被引量：1
-
8Kopp CW, Holzenbein T, Steiner S, et al. Inhibition of restenosis by tissue factor pathway inhibitor: in vivo and in vitro evidence for suppressed monocyte chemoattraction and reduced gelatinolytic activity[J]. Blood, 2004, 103(5): 1653-1661. 被引量：1
-
9Tang XF, Liu JJ, Wu YJ, et al. Effect of hirulog-like peptide on balloon catheter injury-induced neointimal formation in femoral arteries of minipigs and relationship with inflammatory mediators [J]. J Vasc Res, 2010, 47(3): 262-269. 被引量：1
-
10Drachman DE, Simon DI. Inflammation as a mechanism and therapeutic target for in-stent restenosis [J]. Curr Atheroscler Rep, 2005, 7(1): 44-49. 被引量：1
二级引证文献3
-
1尹世敏,王磊,陈红,李秋俐,刘丽娟,徐芳.丹红注射液治疗后循环缺血性眩晕临床观察[J].中国医药,2012,7(12):1609-1609. 被引量：2
-
2成雪,王意忠,丁明超,崔晓兰,王斌,王嘉,时翰,王立梅.骨髓间充质干细胞联合益气养阴化瘀中药干预糖尿病下肢动脉再狭窄模型犬[J].中国组织工程研究,2014,18(18):2872-2879. 被引量：6
-
3谷温雯,吕杰强.TFPI-2在宫颈癌组织中的表达及其与VEGF、MVD的相关性研究[J].药物生物技术,2020,27(3):217-220. 被引量：3
-
1李杨,张廷胜.组织因子途径抑制物的研究进展[J].中国医学创新,2011,8(30):153-155.
-
2张少峰,王廷会,魏宇淼,李伟.老年人冠心病与凝血因子VII基因多态性的关系[J].中华老年医学杂志,2004,23(9):665-667. 被引量：5
-
3“坏血脂”当道,中风临近[J].家庭医药（就医选药）,2010(7):29-29.
-
4荆腊滢,张月芳,郑田春,李震宇.外源性凝血途径和内皮细胞损伤与动脉粥样硬化之间的关系研究[J].中国微循环,2003,7(1):39-40. 被引量：2
-
5陈聪,荆腊滢.外源性凝血途径和内皮细胞损伤与急性心肌梗死之间的关系研究[J].江苏大学学报（医学版）,2003,13(3):213-214.
-
6王建军.高血脂的危害及防治[J].大众健康,2014,0(8):42-43.
-
7金梅花,徐清斌,薛莉.急性冠脉综合征患者血浆TF水平的变化及其临床意义[J].宁夏医学杂志,2008,30(3):205-206.
-
8陆月明,王红.凝血纤溶与急性呼吸窘迫综合征[J].中国急救医学,2004,24(11):831-834. 被引量：3
-
9孙雪峰,苏金环.狼疮性肾炎合并血栓栓塞与抗凝治疗[J].中国实用内科杂志,2009,29(6):507-509. 被引量：2
-
10路亚枫,秦明照.不稳定性心绞痛患者血浆TF、TFPI含量和活性的变化[J].基础医学与临床,2002,22(2):175-176. 被引量：1
