摘要
目的:对郑州市184例严重药品不良反应病例进行分析,为临床安全合理用药提供预警信息和服务。方法:对184例严重药品不良反应报告涉及的药物剂型、给药途径、发生前5位药品进行综合分析。结果:注射剂发生率占90.5%,静脉给药发生率占84.8%;不良反应集中在细辛脑注射液、双黄连注射液或注射用双黄连、注射用头孢曲松钠和注射用头孢哌酮钠舒巴坦钠等。不良反应表现主要是呼吸困难、紫绀、过敏性休克等。结论:提示临床要重视注射液的安全使用和过度使用问题;同样要重视中药注射剂的安全使用问题和肝肾毒性方面的不良反应。
Objective： Zhengzhou City,184 cases of serious cases of adverse drug reaction analysis of clinical safety for the rational use of drugs to provide early warning information and services.Methods： 184 cases of serious adverse drug reaction reports to the drug dosage forms,routes of administration took place before the five drugs comprehensive analysis.Results： The incidence of injection accounted for 90.5%,the incidence of intravenous drug delivery accounted for 84.8%;adverse reactions focused on Asarone injection,injection and injection Shuanghuanglian,Ceftriaxone Sodium for Injection Cefoperazone Sodium and Sulbactam Sodium for Injection.Adverse performance is largely difficulty in breathing,cyanosis,allergic shock.Conclusion： Injection of clinical attention should be paid the safe use and excessive use;also should pay attention to the safe use of traditional Chinese medicine injection problems and liver and kidney toxicity of adverse reactions.
出处
《中医学报》
CAS
2011年第1期94-96,共3页
Acta Chinese Medicine
基金
河南省教育厅自然科学基础研究计划项目(编号:2010A360020)
关键词
药物不良反应
药物剂型
给药途径
adverse drug reaction
dosage form
method of administration
