摘要
目的探讨腹部外科感染性疾病病原菌的构成比和药物敏感率的变化。方法采用美国ＢＤ公司生产的６Ｂ和７Ｄ两种增菌瓶采集标本和培养细菌，并用该公司生产的生化板和药敏板对腹部外科常见的感染性疾病患者共２６９例，进行细菌学和药物敏感度的检测。结果２６９例标本，其中２０６例标本细菌培养阳性，阳性率为７６６％。１８５例标本检出需氧菌共２７１株，检出率为６８８％，以埃希大肠杆菌为主（１１２株）占需氧菌总数的４１３％，其次是变形杆菌（１４４％），肠球菌（６３％）；１４１例标本厌氧菌培养阳性，共检出２９６株菌，总检出率为５２４％，平均每例２１株，以脆弱类杆菌最多共１２９株，占厌氧菌的４３６％，其中又以脆弱拟杆菌为主（６３株），其次是吉氏拟杆菌（２８株）。所有阳性标本中单纯需氧菌和单纯厌氧培养阳性率分别为３１６％和１０２％，而混合感染阳性率为５８３％。革兰阴性（简称Ｇ阴性）菌占主要地位，为需氧菌的７３１％和厌氧菌的６８２％。需氧菌对三代头孢菌素敏感率在８０％～１００％，而对氨基甙类敏感率在３２７％～５００％间，厌氧菌对甲硝唑敏感率达９４６％，氯洁霉素为８５．０％。结论所有菌种都是人体正常菌种，条件致病?
Objective To
investigate the infectious rates of pathogenic bacteria and their drug sensitivity in common
infection diseases of abdominal surgery in local hospitals. MethodsBZThe specimen from 269
cases with the common infectious diseases of abdominal surgery were collected and cultivated
on two types of enrichment bottles, 6B and 7D, which were made by the BD company in
America. At the same time, we used the biochemical and drug sensitive plates to identify the
types of bacteria and their drug sensitivities. HZ Results Among 269 specimen,cultures were
positive in 206 (766%). 271 strains of aerobes were found in 185 specimen, with an incidence of
688%, among which E.coli(112 strains) came first (413%), then proteus (144%) and Enterococcus
(63%). 269 strains of anaerobes were found in 141 specimen, with an incidence of 524% and 2.1
strains per case, the most common type was B.fragilis (63 strains), followed by B.distasonis
(28 strains). In the positive cases, unitary aerobic and unitary anaerobic infection rates were
only 316% and 102% respectively while mixed infection rate was 583%. Most of the pathogens
were gramnegative, 711% in aerobes and 682% in anaerobes. The drug sensitive rate of
aerobes to the 3rd generation cepholosporine were between 80% and 100% and between 327%
and 50% aminoglycocide. 946% of anaerobes were sensitive to metronidazole and 85% to
Clindamycin. HZConclusions All pathogenic bacteria were of normal bacteria in human body.
Infections complicated by abdominal surgery were characterized by opportunistic and
endogenous pathogens. The most common types were mixed infections of aerobic and
anaerobic bacteria. There were more anaerobic infections and most of pathogenic bacteria were
gramnegative, but drug resistant strains were relatively less in Kumming area than in other
出处
《中华普通外科杂志》
CSCD
1999年第4期292-296,共5页
Chinese Journal of General Surgery
关键词
腹部外科
感染
细菌
微生物
药敏试验
AbdomenSurgery,operativeInfectionBacteriaMicrobial sensitivity tests
