摘要
腹型肥胖是脂肪组织主要积聚于腹腔内脏周围的一种肥胖类型,内脏脂肪堆积导致代谢紊乱和心血管疾病发生的作用独立于整体脂肪含量,彰显了腹型肥胖在代谢综合征(MS)中的重要地位。脂肪细胞因子介导的炎症反应是腹型肥胖致胰岛素抵抗进而发展成MS的重要原因。腰围测量简便,与内脏脂肪水平、胰岛素抵抗、心血管疾病风险的相关性均明显强于体质指数(BMI),已成为衡量腹型肥胖的最常用指标,而腰围身高比(WHtR)因其特有的优势,在儿科临床应用前景广阔。关注儿童青少年腹部脂肪堆积,在新近公布的我国儿童青少年腰围正常值基础上,尽快确定异常界值点,早期筛查,及早干预,对预防MS及相关并发症的发生、提升人群健康水平有重要意义。
Visceral obesity is a special type of obesity in which the adipose tissue mainly accumulates around the viscera.Visceral fat mass is a significant and independent determinant of metabolic disturbance and cardiovascular disease,thus visceral obesity plays an important role in the occurrence of metabolic syndrome.The unbalanced secretion of adipocytokines and inflammatory cytokines has been demonstrated to be related to insulin resistance and metabolic syndrome.Waist circumference,which can be easily measured,is more strongly linked to visceral adipose tissue,insulin resistance,and cardiovascular disease than body mass index and it has been a common anthropometric index in evaluating visceral obesity.Waist-to-height ratio might be used widely in the future because of its special advantages.It is urgent to complete the waist circumference database and set standard criteria for diagnosing visceral obesity in Chinese children and adolescents based on the recently proposed normal value of waist circumference in China.The set of criteria is also important for screening,early intervention,preventing metabolic syndrome and other related complication,and finally raise the health standard of people in China.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2010年第12期1113-1116,共4页
Journal of Clinical Pediatrics
基金
浙江省重大与高发疾病防治技术专项基金项目(No.2008C03002-1)
十一五国家科技支撑计划(No.2009BAI80B01)
关键词
腹型肥胖
代谢综合征
儿童青少年
腰围
visceral obesity
metabolic syndrome
children and adolescents
waist circumference
