摘要
本文用Ｘ射线衍射、傅里叶变换红外光谱、差热分析等物理方法研究了抗癌药物铂络合物特性、结构以及构效关系．研究结果表明：ｃｉｓ－［Ｐｔ（ＮＨ３）２Ｃｌ２］属简单斜方晶系，晶格常数ａ＝０．９２２１ｎｍ，ｂ＝０．８７７１ｎｍ，ｃ＝０．６８９０ｎｍ．草酸二氨合铂的结构为斜方晶系，其晶格常数为：ａ１＝１．０７２１ｎｍ，ａ２＝０．６４０２ｎｍ，ａ３＝１．８５７０ｎｍ，并用傅里叶变换红外光谱、差热分析。
Employing X ray diffraction,Fourier transformation infrared spectrum and differential
thermalanalysismethods,theproperties,structuresandstructure
effectrelationofplatinumanticancer complexes are investigated in this paper.The current
research results show that cis[Pt(NH 3) 2Cl 2]is a monoclinic lattice,the corresponding crystal
constants read:a=0.9221nm,b=0.8771nm,c= 0.6890nm.The structure of oxalic platoammine is a
triclinic lattice,the crystal constants are a 1= 1.0721nm,a 2=0.6402nm,a 3=1.8570nm.It′s
chemical and physical properties are studied by the optical methods mentioned previously.
出处
《光子学报》
EI
CAS
CSCD
1999年第5期440-442,共3页
Acta Photonica Sinica
基金
国家自然科学基金
