摘要
目的对血浆钢＜130mmol／L，利尿剂作用减弱，腹水消失时间延长的56例肝硬化腹水病人，静脉输往3％NaCl观察尿量变化及腹水消失时间。方法根据血浆钠检测结果，日补充3％Na－Cl溶液300ml，连续使用1～7d，平均每人输往455．8ml。结果输往高渗NaCl后6h尿量开始增加，24h增加500ml～1500ml，腹水消失时间8～20d，平均13d，腹水消失时间与限钠治疗患者（139例）相比明显缩短。结论肝硬化腹水限钠、利尿治疗可使血浆钠及渗透压下降，因尿钠排出减少，使利尿剂作用减弱或消失，腹水消失时间延长并诱发低渗性脑病等，因此应对肝硬化腹水限钠问题进行重新评价。
Objective Observe the urine volume changement and the hydroperitoneum disappear-ing by using NaCl (3%) venous infusing to 56 cases with cirrhotic hydroperitoneum(plasma sodium<130mmol/L). Methods According to the test result, in 1-7 days, by using NaCl(3%) venous infusing 300ml everyday, the average in per person is 455. 8ml. Results The urine volume begins to increase af-ter 6 hour hypertonic NaCl infusion. The volume comes t0 500-1500ml after 24 hours. The hydroperi-toneum disappearing time is 8-20 days, the average of which is 13 days. The hydroperitoneum disap-pearing time is shortened distinctly, compared with that of Na-restriction in 139 cases. Couclusion Na-limit and diuretic treatment on cirrhotic hydroperitoneum can decrease the plasma sodium and os-motic pressure. Because of the decreasing of the urine Na excretion, the effectiveness of the diuretic has been weakened or disappeared, the hydroperitoneum disappearing time prolonged and hypotonicity en-cephalopathy disease may be induced, etc. Therefore the problem about Na-limit on cirrhotic hydroperi-toneum patients should be reappraised.
出处
《中国全科医学》
CAS
CSCD
1999年第2期118-119,共2页
Chinese General Practice
关键词
肝硬化
腹水
高渗氯化钠
血浆钠
渗透压
Cirrhotic hydroperitoneum
Hypertonic
NaCl
Plasma sodium
Osmotic pressure
