摘要
低温微波技术可用于降低微波反应时体系的温度,减少或消除微波辐射时速热效应带来的副反应,具有快速高效、反应均匀、安全环保等优势,在化学研究中得到了广泛关注和应用。本文介绍了低温微波技术的实现方法,综述了近年来该技术在蛋白质研究、合成反应、天然产物研究和微波化学机理研究等领域中的应用,并展望了低温微波技术的发展方向。
Low temperature microwave technique develops normal microwave heating technique and expanded its application range. The technology can reduce or eliminate the side reaction caused by sever thermal effects. There are several approaches used to achieve low temperature, such as adjusting the microwave radiation source, cooling medium, change of the reactants physical property and controlling the initial temperature of reactants. Low temperature microwave technique is applied widely for its high speed, security, reaction uniformity in chemistry research. By this new technique, some proteins can exposure under microwave radiation without protein denaturation, some catalytic synthesis can achieve higher yield and higher reaction rate than that in normal microwave reaction and some natural products can be extracted under protection from decomposition and oxidization. In addition, this technique can also be used as a tool to research microwave chemical mechanism. In this paper, the low temperature microwave technique is introduced and its application in protein research, catalytic synthesis, natural products research and microwave chemical mechanism research are reviewed. The future development of low temperature microwave technique is prospected.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2010年第12期2462-2468,共7页
Progress in Chemistry
基金
国家自然科学基金项目(No.20905080
20375050)
"十一五"国家科技支撑计划重点项目(No.2006BAK03A08)
广东省科技计划项目(No.2009B010900021)资助
关键词
低温微波技术
蛋白质
催化合成
天然产物
微波化学机理
low temperature microwave technology
proteins
catalytic synthesis
natural products
microwave chemical mechanism
