摘要
建立了兽医透皮吸收新型制剂恩诺沙星搽剂中恩诺沙星紫外分光光度测定法，用初均速法探讨其稳定性．结果表明，用紫外分光光度法测定制剂含量平均回收率为１００．４０％ ， Ｒ Ｓ Ｄ 为０．１３％ ．初均速法预测本制剂２５ ℃贮存有效期为 ２．２８ ａ，这说明该搽剂处方合理，稳定性良好，质量可靠．紫外分光光度法测定恩诺沙星搽剂含量快速简便，精确度好．
A ultraviolet spectrophotometry used for veterinary medication via transdermal absorption was established to measure the content of enrofloxacin in the liniment. The stability of enrofloxac in liniment was studied by use of the method of initial average rate. The result measured by the ultra violet spectrophotometry showed that the average recovery rate of enrofloxacin from the liniment was 100.40%, and the average relative standard deviation (RSD) was 0.13%. The shellife of enrofloxacin liniment at 25 ℃ measured by the initial average rate method was 2.28 a. The analysis method of the ultraviolet spectrophotometry was rapid and precise.
出处
《福建农业大学学报》
CSCD
1999年第2期196-199,共4页
Journal of Fujian Agricultural University
关键词
恩诺沙星搽剂
紫外分光光度法
初均速法
稳定性
enrofloxacin liniment
ultraviolet spectrophotometry
initial average rate method
stability
