摘要
转录因子与顺式作用元件结合,可调控下游一系列基因的表达。通过基因工程手段使一个抗病转录因子基因在植物中超表达就相当于转入了多个抗病基因,从而提高综合抗病能力,因此,转录因子已成为近年来的研究热点。综述了乙烯应答元件结合因子(Ethylene-responsive element binding factors,AP2/EREBP)、MYB、WRKY、碱性亮氨酸拉链[Basic(region-leucine)Zipper,bZIP]家族和homeodomain蛋白5种植物抗病相关转录因子的结构、功能特性、调控机制以及它们在植物抗病基因工程方面的研究成果,并展望了其应用前景。
Transcription factors binding to cis-elements can regulate series of downstream gene expression.The over-expression of a disease-resistance transcription factor in plants which can improve comprehensive disease resistance by means of genetic engineering correspond to transgenic a number of resistance genes.They have become a research hotspot in recent years.Five families of transcription factors that are related to disease resistance（AP2/EREBP,MYB,WRKY,bZIP and homeodomain）were introduced,and their protein structure,functional properties,regulation mechanisms,their research progress on gene engineering of diseases resistances in plants,their applications were discussed.
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2010年第10期94-99,共6页
China Biotechnology
基金
国家自然科学基金(30972001)资助项目
关键词
转录因子
植物抗病
基因工程
调控机制
Transcription factor Plant disease resistance Genetic engineering Regulation mechanisms
