摘要
目的:探讨慢性前列腺炎(CP)患者服用5α-还原酶抑制剂-爱普列特后前列腺炎症积分指数的影响。方法:选择110例患者,其中2型前列腺炎(CBP)40例,3型前列腺炎(CNBP)70例。给予左氧氟沙星200mg,每日两次治疗的同时,加用爱普列特5mg,每日2次,疗程6周。用药前后均行前列腺炎症积分指数评分。结果:95例患者疼痛、排尿异常和对生活质量的影响评分明显下降。组为疼痛症状评分为(16±3.2),排尿评分为(7±2),生活质量评分为(8±3);治疗6周后患者治疗前其中CBP组疼痛症状评分为(6±2.2),排尿评分为(3±1),生活质量评分为(4±2),cnbP组为疼痛症状评分为(5±1.8),排尿评分为(4±1.5),生活质量评分为(4±2.1);评分越高,治疗后评分改善越理想(P<0.05)。结论:患者前列腺炎症状积分指数可以较为客观反映患者的症状,联合应用爱普列特及左氧氟沙星治疗6周后,可以明显改善患者症状,本组研究中未出现不良反应。未发现2,3型前列腺炎有显著差异。
Objective：To evaluate the effect of epristeride,a 5areduetase inhibitor, in the treatment of chronic non-bacterial p rostatitis. Methods： 110 patients with Chronic prostatitis were recruited,among them, 40 patients were chronic bacterial prostatitia（CBP）and 70 were chronic nonbaeterial prostatitia（CNBP）.200 mg Levofloxaein and 5 mg Epristeride,were administered twice a day for 6 weeks.Before and after the treatment,the patients N IH-CPSI were evaluated.Results：95 patients with their pain index,Urination index and life quality index decreased significantly.In the CNBP group,the average pain index decreased from （160±3.2） to （4±1.8）;the average urination index decreased from （7±2） to （2±1.5）;the average life quality index decreased from （8±3） to （2.5±1. 1）.In the CBP group,the average pain index decreased from （12±3.5） to （4±2.2）;the average urination index decreased from （6±2） to （2±1）;the average life quality index decreased from 7±3）to （2±1.2）.Patients who have higher symptom index before the treatment experienced more obviously improvement in their symptom （P〈0.05）.Conclusion：NIH-Chronie Prostatitis Symptom Index can reflection Prostatitis＇s symptom objectively.Epristeride in combination with an antibiotic can effectively relieve the pain and urination symptoms and improve the life quality of the patients with chronic prostafitis. No serious side effects were recorded during the study.
出处
《中国医药导刊》
2010年第10期1725-1726,共2页
Chinese Journal of Medicinal Guide
