摘要
目的探讨经颅多普勒超声微栓子信号在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并脑梗死患者中的表现。方法采用多通道经颅多普勒超声进行42例健康志愿者双侧大脑中动脉的监测,40例单纯OSAHS、42单纯脑梗死以及39例OSAHS合并脑梗死患者经颅多普勒超声微栓子信号(MES)检测。结果脑梗死组、OSAHS组、OSAHS+脑梗死组MES明显高于正常对照组(P<0.01);OSAHS+脑梗死组MES高于脑梗死组(P<0.01),也高于OSAHS组(P<0.01)。结论 OSAHS患者MES增高可能是导致脑梗死发生的原因之一。对OSAHS患者的MES进行干预可作为OSAHS的辅助治疗方法,对预防脑梗死的发生及发展也有一定的临床意义。
Objective To discuss the role of MES in the relation between obstructive sleep apnea-hypopnea syndrome and cerebral infarction.Methods TCD was used to detect the MES in 42 healthy volunteers,40 cases of OSAHS,42 cases of cerebral infarction and 39 cases of OSAHS with cerebral infarction.Results The MES of cerebral infarction group,OSAHS group and OSAHS with cerebral infarction group were significantly higher than that of the normal group（P0.01）;in OSAHS with cerebral infarction group,the MES was not only higher than that of cerebral infarction group（P0.01）,but also higher than that of OSAHS group（P0.01）.Conclusions The increased MES may be one of the reasons leading to cerebral infarction.The decreased MES number of OSAHS patient could be used as adjuvant therapy for OSAHS,and this has the clinical significance in prevention of occurrence and development of cerebral infarction.
出处
《卒中与神经疾病》
2010年第5期277-279,共3页
Stroke and Nervous Diseases
