摘要
目的对两种评估脑白质疏松的方法进行比较,探讨脑白质疏松与脑萎缩的关系。方法 45例磁共振成像(MRI)提示脑白质疏松但无残障的老年住院患者。应用评价胆碱能神经纤维通路脑白质疏松CPHIS量表和全脑白质疏松Scheltens量表分别评估头颅MRI脑白质疏松的严重程度,并与脑萎缩指标进行Spearman相关分析。结果 45例无残障脑白质疏松患者CPHIS量表评分(27.18±20.26),Scheltens量表评分(19.87±11.69)。脑白质疏松CPHIS评分与皮层脑沟宽度呈正相关(r=0.341,P<0.05);Scheltens量表评分与脑室指数呈正相关(r=0.320,P<0.05),与皮层脑沟宽度呈正相关(r=0.325,P<0.05)。结论皮层脑萎缩主要与胆碱能神经纤维的脑白质疏松有关。
Objective Comparing two methods of the leukoraiosis and cerebral atrophy,to investigate the correlation of the leukoaraiosis and cerebral atrophy in the elderly nondisaility people.Methods Analysis the relationships between the scores of leukoraiosis by CPHIS,Scheltens scales and of the cerebral atrophy in the 45 elderly nondisaility subjects with leukoraiosis in hospital.Results In the 45 elderly nondisaility subjects,the score of leukoraiosis by CPHIS were（27.18±20.26）,the the scores of leukoraiosis by Scheltens scales were（19.87±11.69）.There was positive correlation between the the scores of CPHIS and CSW（Cortical sulcus width）（r=0.341,P0.05）.There was positive correlation between the the scores of Scheltens scales and CSW（r=0.325,P0.05）,and VI（ventricle index）（r=0.320,P0.05）.Conclusion The leukoraiosis on the Cholinergic Pathways may have a relationships with the CSW.
出处
《中华脑血管病杂志（电子版）》
2010年第5期11-14,共4页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
关键词
脑白质疏松
脑萎缩
Leukoaraiosis
Cerebral atrophy
