摘要
目的:探讨注射用阿魏酸钠联合归芪固肾饮治疗糖尿病肾病疗效。方法:98例糖尿病肾病患者随机分成3组,患者均予优质低蛋白糖尿病饮食,适当运动,根据血糖水平给予胰岛素强化治疗,高血压者缬沙坦80 mg qd口服,阿魏酸钠对照组在此基础上加用注射用阿魏酸钠,14 d为1个疗程,共用3个疗程。治疗组在此基础上加用注射用阿魏酸钠联合归芪固肾饮治疗,疗程同阿魏酸钠对照组。进行评价疗效。结果及结论:治疗组治疗前后空腹血糖(FBG),24 h尿蛋白定量,血尿素氮(BUN),肌酐(Scr),血浆白蛋白(Alb)比较,差异均有非常显著性(P<0.05或P<0.01);对照组仅FBG,24 h尿蛋白定量治疗前后比较,差异有显著性(P<0.05或P<0.01);治疗后各项指标比较,治疗组明显优于阿魏酸钠对照组,差异有显著性(P<0.05)。显示注射用阿魏酸钠联合归芪固肾饮治疗和延缓糖尿病肾病的进展中有协同作用,疗效明显。
Objective：To study the injection of sodium ferulate combined with Cordyceps Gushen Guiqi drink diabetic nephropathy.Method：Ninty-eight Patients were randomLy divided into three groups of diabetic nephropathy after admission all patients high-quality low-protein diabetic diet,adequate exercise,according to blood glucose levels to metformin 1.0-1.5 g.d-1 or glipizide up to 15-75 mg.d-1,hypertension Captopril 25-75 mg.d-1 divided 2-3 times orally,the control group with sodium ferulate was based on the use of sodium ferulate,14 days to a course of treatment,sharing 3 courses.the treatment group was based on the use of sodium ferulate combined injection Cordyceps Guiqi Gushen drink,14 days to a course of treatment,sharing 3 courses were evaluated.Result：Before and after treatment FBG,24 h urinary protein,blood BUN,Scr,serum Alb comparison,the differences were very significant（P《0.05 or P 0.01）;control group FBG,24 h urinary protein before and after treatment,There was a significant difference（P《0.05 or P 0.01）;the indicators after treatment compared to the treatment group than the control group,the difference was significant（P《0.05） shows injection of sodium ferulate combined Cordyceps Guiqi Gushen drink treatment and delay the progression of diabetic nephropathy in synergy,efficacy significantly.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第14期196-198,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
糖尿病肾病
注射用阿魏酸钠
归芪固肾饮
diabetic nephropathy
sodium ferulate injection
Cordyceps Gushen Guiqi drink
